Diseases accompanied by hypocalcemia, increased permeability of cell membranes, impaired nerve impulses in muscle tissue. Hypoparathyroidism (latent tetany, osteoporosis), impaired metabolism of vitamin D (rickets, spasmophilia, osteomalacia), hyperphosphatemia in patients with chronic renal failure. Increased need for calcium (period of intensive growth of children and adolescents; pregnancy, breastfeeding period), insufficient Ca2 + content in food, impaired metabolism in the postmenopausal period, bone fractures. Increased excretion of Ca2 + (prolonged fasting, chronic diarrhea, hypocalcemia with prolonged diuretics, antiepileptic drugs, glucocorticosteroids). In complex therapy: bleeding of different etiologies, allergic diseases (serum sickness, urticaria, catarrh syndrome, itching dermatoses, angioneurotic edema); bronchial asthma, dystrophic alimentary edema, pulmonary tuberculosis, eclampsia, parenchymal hepatitis, toxic liver damage, nephritis. Poisoning with magnesium salts, oxalic acid, soluble salts of fluoric acid (insoluble and non-toxic calcium oxalate and calcium fluoride are formed upon interaction with calcium gluconate).