Adults and children aged 10 and over. Primary hypercholesterolemia (type IIA, including heterozygous familial hypercholesterolemia) or mixed dyslipidemia (type IIB) as an adjunct to the diet, when adherence to the diet and the use of other non-medicinal means (such as exercise, weight loss) are insufficient.
Homozygous familial hypercholesterolemia as an adjunct to diet and other low-dose treatments (such as LDL apheresis) or in cases where such treatments are inappropriate.
Prevention of cardiovascular disorders.
Prevention of significant cardiovascular disease in patients who are estimated to be at high risk for the first case of cardiovascular disease, in addition to correcting other risk factors.