To relieve symptoms of nausea and vomiting.
DOMIDON COMPOSITION OF THE MEDICINAL PRODUCT:
active substance: domperidone 1 tablet contains domperidone 10 mg
excipients: lactose monohydrate, corn starch, microcrystalline cellulose, pregelatinized starch, povidone, magnesium stearate.
Film casing: Sepifilm 752 Blanc.
DOMIDON DOSAGE FORM.
Film-coated tablets Film-coated tablets, white or almost white, round with a biconvex surface
DOMIDON PHARMACOTHERAPEUTIC GROUP.
Peristalsis stimulants (propulsants). ATC code А03F A03.
The mechanism of action is due to the blockade of dopamine (D2) receptors, thereby eliminating the inhibitory effect of dopamine on the motor function of the gastrointestinal tract. Increases the duration of peristaltic contractions of the antrum of the stomach and duodenum, accelerates gastric motility, increases the tone of the lower esophageal sphincter. Does not affect gastric secretion. It has an antiemetic effect due to a combination of gastrokinetic effect and antagonism to dopamine receptors in the chemoreceptor trigger zone located outside the blood-brain barrier. Eliminates hiccups and nausea.
INDICATIONS FOR USE.
Adults. Nausea and vomiting, epigastric fullness, pain in the upper abdomen, heartburn with or without discharge of stomach contents into the mouth.
Hypersensitivity to domperidone or to any of the components of the drug.
Cases where stimulation of the motor function of the gastrointestinal tract can be dangerous (for example, gastrointestinal bleeding, mechanical intestinal obstruction, perforation of the stomach or intestines).
Patients with a prolactin-secreting pituitary tumor (prolactinoma).
PROPER USE SAFETY.
Domidon should not be taken simultaneously with antacids or antisecretory drugs.
The drug contains lactose, so it should not be prescribed to patients with rare hereditary forms of galactose intolerance, lactase deficiency or glucose-galactose malabsorption syndrome.
Domperidone should be used with caution in patients with a risk factor for prolongation of the QT interval, including hyperkalemia, severe hypermagnesemia, organic heart disease, and concomitant use of drugs that prolong the QT interval.
Application during pregnancy or lactation.
Domidon is not recommended for use during pregnancy. The drug passes into breast milk, therefore it is not recommended to use the drug during breastfeeding.
ABILITY TO INFLUENCE THE RATE OF REACTION WHEN DRIVING A VEHICLE OR WORKING WITH OTHER MECHANISMS.
You should refrain from driving motor vehicles and working with other mechanisms during drug treatment.