Efferalgan (paracetamol) suppositories 150 mg. №10


Manufacturer: France

Symptomatic treatment of diseases accompanied by mild to moderate pain and / or fever.



Efferalgan suppositories Composition
The active ingredient is paracetamol (1 rectal suppository contains 150 mg of paracetamol).

The excipient is solid fat.

Efferalgan suppositories Contraindications
hypersensitivity to paracetamol or other components of the drug;
age up to one month (body weight of a child up to 4 kg);
severe renal and / or liver dysfunction, hepatocellular insufficiency, congenital hyperbilirubinemia, glucose-6-phosphate dehydrogenase deficiency, alcoholism, blood diseases, severe anemia, leukopenia;
inflammation of the rectal mucosa and dysfunction of the anus, rectal bleeding;
do not use for diarrhea.

Efferalgan suppositories Mode of application
The drug should be used under medical supervision, with extreme caution – for children under one year of age. Apply rectally.

Suppositories cannot be split to obtain the required dosage. If, when calculating the daily dose in accordance with the child’s body weight, a single dosage is required, less than the contents of one suppository, then after consulting a doctor, it is recommended to use other dosage forms of paracetamol (for example, oral solution).

When treating children, the dose calculation mode should be observed in accordance with the child’s body weight and, depending on this, an acceptable dosage form should be chosen.

The approximate age of children based on body weight is a guideline only.

Rectal suppositories 150 mg are intended for children weighing from 8 to 12 kg (aged approximately 6 months to 2 years). From 3 to 4 suppositories per day with an interval between doses of 6 hours, depending on the child’s body weight, at the rate of 60 mg / kg / day.

The recommended daily dose of paracetamol is about 60 mg / kg / day, which should be divided into 4 doses, that is, 15 mg / kg of body weight every 6 hours. With severe renal failure (creatinine clearance less than 10 ml / minute), the interval between doses should be at least 8 hours.

Application involves the introduction of rectally one suppository, which is repeated, if necessary, with an interval of at least 6 hours, but not exceeding the daily dose and the number of 4 suppositories per day.

Due to the risk of local toxicity, the use of suppositories more than 4 times a day is not recommended, and the duration of use with the rectal route of administration should be the shortest.

Application features
The drug in this dosage form is used only for children.

The drug in this dosage form is used only for children.

To avoid overdose, do not use other medicines containing paracetamol. There is a risk of overdose in young children. This can be fatal.

Urgent measures: immediate hospitalization; determination of the level of paracetamol in blood plasma; gastric lavage; the introduction of the antidote N-acetylcysteine ​​or methionine orally within the first 10 hours; symptomatic therapy.

Side effects
Very rarely:

allergic reactions: anaphylaxis, anaphylactic shock, Quincke’s edema, erythema, urticaria, pruritus, rash on the skin and mucous membranes, exudative erythema multiforme, toxic epidermal necrolysis;
on the part of the hematopoietic organs: anemia, sulfhemoglobinemia and methemoglobinemia (cyanosis, shortness of breath, heart pain), hemolytic anemia, thrombocytopenia, leukopenia and neutropenia;
from the respiratory system: bronchospasm in patients sensitive to aspirin and other NSAIDs;
from the digestive system: nausea, epigastric pain, abnormal liver function, increased activity of liver enzymes, usually without the development of jaundice, hepatonecrosis (dose-dependent effect);
from the endocrine system: hypoglycemia, up to hypoglycemic coma.
Associated with the dosage form: irritation of the rectum and anus.

If any undesirable reactions occur, you should stop using the drug and be sure to consult a doctor.