Treatment and prevention of intestinal dysbiosis and associated endogenous dysvitaminosis. Therapy aimed at restoring the normal intestinal microflora, which is disturbed during treatment with antibiotics or chemotherapy drugs. Acute and chronic gastrointestinal diseases associated with intoxication or intestinal dysbiosis and dysvitaminosis in infants who are fed breast milk.
active substance: 1 bottle of 5 ml contains spores of the multidrug-resistant strain of Bacillus clausii – 2 × 109;
auxiliary substances: purified water.
Enterogermina Dosage form
Basic physical and chemical properties: whitish opalescent liquid, which may have a characteristic odor.
Enterogermina Pharmacological group
Antidiarrheal microbial drugs.
ATX code A07 FA.
Enterojermina® is a suspension of Bacillus clausii spores, which are usually present in the intestine and do not show pathogenic activity.
Thanks to the action of Bacillus clausii, the drug restores the intestinal microflora, altered as a result of treatment with drugs that lead to dysbiosis. In addition, due to the ability of Bacillus clausii to synthesize various vitamins, especially of group B, the drug helps to correct dysvitaminosis caused by the use of antibiotics or chemotherapy drugs. Due to the metabolic activity of Bacillus clausii, the use of the drug makes it possible to achieve a nonspecific antigenic and antitoxic effect.
Due to their high resistance to chemical and physical agents, spores of Bacillus clausii pass intact through the gastric juice barrier into the intestinal tract, where they are converted into metabolically active vegetative cells.
There is no data.
Treatment and prevention of intestinal dysbiosis and associated endogenous dysvitaminosis.
A therapy aimed at restoring normal intestinal microflora, which is disturbed during treatment with antibiotics or chemotherapy drugs.
Acute and chronic gastrointestinal diseases associated with intestinal intoxication or dysbiosis and dysvitaminosis in infants who are fed with breast milk.
Hypersensitivity to the active substance or to any of the excipients of the drug.
Special security measures
Vials with Enterogermina® may contain visible particles formed as a result of aggregation of Bacillus clausii spores and, accordingly, do not indicate that the preparation has undergone any changes.
Shake the bottle before use.
The drug has a high degree of heterologous resistance to antibiotics, which makes it possible to use it both for the prevention of changes in the intestinal microflora caused by the selective action of antibiotics (especially broad-spectrum antibiotics) and for the restoration of an already disturbed balance of the intestinal microflora.
The drug does not interact with such antibiotics: penicillin when used not in combination with beta-lactamase inhibitors, cephalosporins (partial resistance in most cases), tetracyclines, macrolides, aminoglycosides (with the exception of gentamicin and amikacin), chloramphenicol, thiamphenicol, lincomycin, isoniazidamide , cycloserine, novobiocin, rifampicin, nalidixic acid and pipemidic acid (intermediate resistance), metronidazole.
If the drug is prescribed concurrently with antibiotics, it should be used between two antibiotic doses.
This medicinal product is intended for oral use only. It is forbidden to inject the drug by injection or any other way. Inappropriate use of this drug has resulted in severe anaphylactic reactions such as anaphylactic shock.