Ergos (sildenafil) tablets 50 mg. №8


Manufacturer: Ukraine

ERGOS is recommended for men with erectile dysfunction, which is defined as the inability to achieve or maintain an erection of the penis necessary for successful sexual intercourse. For the effective action of ERGOS, sexual arousal is necessary.



Ergos №8 Composition
active substance: sildenafil;

1 tablet contains 50 mg of sildenafil;

Excipients: lactose monohydrate, magnesium gluconate, powdered sugar, calcium stearate, flavor “Lemon”, tartrazine dye (E 102).

Ergos №8 Dosage form


Main physical and chemical properties: biconvex yellow tablets with a dotted line on one side and the company logo on the other.

Pharmacotherapeutic group

Remedies used for erectile dysfunction. Sildenafil.

Pharmacological properties

Ergos №8 Pharmacodynamics.

Mechanism of action.

Sildenafil is an oral drug used to treat erectile dysfunction. During sexual arousal, the drug restores reduced erectile function by increasing blood flow to the penis.

The physiological mechanism that causes an erection involves the release of nitric oxide (NO) in the corpora cavernosa during sexual arousal. The released nitric oxide activates the enzyme guanylate cyclase, which stimulates an increase in the level of cyclic guanosine monophosphate (cGMP), which in turn causes relaxation of the smooth muscles of the corpora cavernosa, promoting blood flow.

Sildenafil is a potent and selective inhibitor of cGMP-specific phosphodiesterase 5 (PDE-5) in corpora cavernosa, where PDE-5 is responsible for the breakdown of cGMP. The effect of sildenafil on erection is peripheral. Sildenafil does not have a direct relaxing effect on isolated human corpora cavernosa, but strongly enhances the relaxing effect of NO on this tissue. Upon activation of the metabolic pathway NO / cGMP, which occurs during sexual stimulation, inhibition of PDE-5 by sildenafil leads to increased levels of cGMP in the corpora cavernosa. Thus, in order for sildenafil to cause the desired pharmacological effect, sexual arousal is required.