Local treatment of fungal infections caused by naftifin-sensitive pathogens: fungal infections of the skin and skin folds; interdigital mycoses; fungal nail infections (onychomycosis); skin candidiasis; pityriasis versicolor; inflammatory dermatomycosis, with or without itching; mycosis of the external auditory canal.
Estezifin spray Composition
active substance: naftifine hydrochloride;
1 ml of spray contains naftifine hydrochloride in terms of 100% dry matter 10 mg;
excipients: propylene glycol, ethanol 96%, purified water.
Estezifin spray Dosage form
Spray for skin.
Basic physical and chemical properties: clear solution from colorless to light yellow with an alcoholic odor.
Antifungal agents for dermatological use. ATX code D01A E22.
Estesifin is an antifungal agent of the allylamine class, the mechanism of action of which is associated with inhibition of the action of ergosterol.
Estesifin is active against dermatophytes such as trichophyton, epidermophyton and microsporum, yeast (Candida), mold (Aspergillus) and other fungi (eg Sporothrix Schenckii). In relation to dermatophytes and aspergil, naftifine in vitro has a fungicidal effect against yeast fungi – it exhibits a fungicidal or fungistatic effect, depending on the strain of the microorganism.
Estesifin also has antibacterial activity against gram-positive and gram-negative microorganisms, which can cause secondary bacterial infections along with mycotic lesions.
In addition, Estesifin has anti-inflammatory properties, which helps to quickly eliminate the symptoms of inflammation and itching.
Due to the rapid penetration of the drug into the skin and the formation of persistent antifungal concentrations in different layers of the skin, Estesifin can be used once a day.
Estezifin spray Indications
Local treatment of fungal infections caused by pathogens sensitive to naftifine:
fungal infections of the skin and skin folds;
fungal infections of the nails (onychomycosis);
inflammatory dermatomycosis, with or without itching.
Hypersensitivity to naftifine or propylene glycol. The drug should not be applied to the wound surface. Do not use to treat eyes.
Interaction with other medicinal products and other types of interactions
There have been no cases of interaction with other drugs.
Apply the drug only externally!
The drug contains ethanol, therefore contact with the eyes and open wounds should be avoided.
The ability to influence the reaction rate when driving or operating machinery
Does not affect.