Floxal eyes ointment 0.3% 3g


Manufacturer: Germany

Infections of the anterior segment of the eye caused by pathogenic microorganisms sensitive to ofloxacin, such as bacterial inflammation of the conjunctiva, cornea, eyelids and lacrimal sac; barley and corneal ulcers.



Floxal Composition
active substance: ofloxacin;

1 g of ophthalmic ointment contains 3 mg of ofloxacin; one dose (1 cm of a strip of ointment) contains 0.12 mg of ofloxacin;

excipients: lanolin, white soft paraffin, liquid paraffin.

Floxal Dosage form
Eye ointment.

Basic physical and chemical properties: light yellow ointment of soft consistency.

Floxal Pharmacotherapeutic group
Means used in ophthalmology. Antimicrobial agents. Ofloxacin. ATX code S01A E01.

Ofloxacin, a quinolone acid derivative, is a fluoroquinolone (gyrase inhibitor), an antibiotic, and has a bactericidal effect.

Limit values

The effectiveness depends on the ratio of the maximum concentration of the drug in the tissues (C max) and the MIC (MIC) for the pathogen.

Animal experiments have shown that, after topical application, ofloxacin can be detected in the cornea, conjunctiva, eye muscle, sclera, iris, ciliary body and in the anterior chamber of the eye. Repeated use also results in therapeutic vitreous concentrations.

After a single application of a strip of ointment approximately 1 cm long (which is equivalent to 0.12 mg of ofloxacin), the maximum concentrations of ofloxacin in the conjunctiva (9.72 μg / g) and sclera (1.61 μg / g) are reached after 5 minutes. Then the concentrations decrease slowly.

After an hour, the concentrations in the intraocular fluid and the cornea reach the maximum values ​​of 0.69 μg and 4.87 μg, respectively.

Infections of the anterior segment of the eye caused by pathogenic microorganisms sensitive to ofloxacin: chronic conjunctivitis, keratitis, corneal ulcer and chlamydial infections.

Hypersensitivity to the components of the drug, other quinolones.

Interaction with other medicinal products and other types of interactions
Unknown. Drug interaction studies conducted with the systemic use of ofloxacin showed that the clearance of metabolites of caffeine and theophylline slightly depends on ofloxacin.

There have been no reports of overdose cases so far.

Treatment is symptomatic, you must immediately rinse the eye (s) with water.