Treatment of such diseases in adults as: – cryptococcal meningitis; the coccidioidomycosis; – invasive candidiasis; – candidiasis of the mucous membranes, including oropharyngeal candidiasis and esophageal candidiasis, candiduria, chronic candidiasis of the skin and mucous membranes; – chronic atrophic candidiasis (candidiasis caused by the use of dentures) with the inefficiency of local dental hygiene products; – vaginal candidiasis, acute or recurrent, when local therapy is not appropriate; – Candida balanitis when local therapy is not appropriate; – dermatomycosis, including mycosis of the feet, mycosis of smooth skin, inguinal dermatomycosis, multi-colored lichen and Candida infections of the skin, when indicated to use systemic therapy; – dermatophytic onychomycosis, when the use of other drugs is not advisable. Prevention of such diseases in adults as: – recurrence of cryptococcal meningitis in patients at high risk of developing it; – relapse of oropharyngeal or esophageal candidiasis in patients with vis with a high risk of developing it; – reducing the frequency of recurrent vaginal candidiasis (4 or more cases per year); – prevention of Candida infections in patients with long-term neutropenia (for example, patients with malignant blood diseases who receive chemotherapy, or patients with hematopoietic stem cell transplantation). Children. You can use the drug in the form of capsules for this category of patients when children are able to safely swallow the capsule, which is usually possible from the age of 5. Fluconazole is used in children for the treatment of mucosal candidiasis (oropharyngeal candidiasis, esophageal candidiasis), invasive candidiasis, cryptococcal meningitis, and for the prevention of candidiasis infections in patients with reduced immunity. The drug can be used as a maintenance therapy to prevent recurrence of cryptococcal meningitis in children at high risk of developing it. Therapy with fluconazole can be started before receiving the results of culture and other laboratory tests; after receiving the results of antibacterial therapy, it should be adjusted accordingly.