Fort-gel 2.5% 30 g.


Manufacturer: Ukraine

Post-traumatic muscle and joint pain, tendovaginitis.



Fort-gel 2.5% Composition
active substance: 1 g of gel contains 0.025 g of ketoprofen;

excipients: ethanol 96%, carbomer, triethanolamine, lavender oil, purified water.

Fort-gel 2.5% Dosage form
Gel 2.5%.

Basic physical and chemical properties: gel is colorless, almost transparent, of uniform consistency, with a fragrant odor.

Fort-gel 2.5% Pharmacotherapeutic group
Topical non-steroidal anti-inflammatory drugs. Ketoprofen.

ATX code М02А А10.

Ketoprofen belongs to NSAIDs (NSAIDs), propionic acid derivatives. It has an analgesic and anti-inflammatory effect due to inhibition of the action of cyclooxygenase 1 (COX-1) and cyclooxygenase 2 (COX-2), inhibition of bradykinin activity, stabilization of lysosomal membranes and inhibition of macrophage migration. Ketoprofen has analgesic and anti-inflammatory effects at an early stage (vascular phase) and at a late stage (cellular phase) of the inflammatory response. Ketoprofen also inhibits platelet aggregation.

When Ketoprofen is applied topically, the gel is absorbed from the skin and penetrates locally into inflammatory tissues. Absorption to systemic circulation is very low (only 5% of the dose is applied).

The preparation applied to the skin quickly penetrates into the problem area and maintains the therapeutic concentration in it. Absorption into the general bloodstream, on the contrary, is slow. When applied to the skin with a gel containing 50 to 150 mg of ketoprofen, after 5-8 hours in the blood plasma, the concentration of the active substance is not more than 0.08-0.15 μg / ml, and has almost no clinically significant effect on the body.

Post-traumatic pain in muscles and joints, tendovaginitis.

Hypersensitivity to ketoprofen or any other excipients of the drug, salicylates and other NSAIDs.

Hypersensitivity reactions are known, for example, symptoms of bronchial asthma, allergic rhinitis or urticaria after the use of ketoprofen, other NSAIDs, acetylsalicylic acid, fenofibrate, tiaprofenic acid. Exacerbation of gastric ulcer or duodenal ulcer. History of gastrointestinal bleeding. Chronic dyspepsia (discomfort and pain in the upper abdomen). Severe renal failure. Skin injuries and diseases, skin trauma, irritation, itching, acne, burns (rash, eczema, skin infections). The gel should not be applied to damaged skin (dermatoses, open and infected wounds). Do not use sealed dressings.

Any history of photosensitivity reactions. A history of skin manifestations of allergies arising from the use of ketoprofen, other excipients of the drug, fenofibrate, tiaprofenic acid, blockers of ultraviolet (UV) rays or perfumes. Influence of sunlight (even on a foggy day), including indirect sunlight and UV radiation in a tanning bed during the entire treatment period and for another 2 weeks after stopping treatment.

Pregnancy (III trimesters), lactation period.