Fortum powder for solution for injections 500 mg. №1

$9.90

Manufacturer: Italy

endoscopic or radiological examination of the large intestine; surgery on the large intestine.

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Description

Fortum powder Storage
active substance: ceftazidime;

1 vial contains ceftazidime (in the form of ceftazidime pentahydrate) 500 mg or 1 g or 2 g;

Excipient: sodium carbonate anhydrous.

Fortum powder Dosage form
Powder for solution for injection.

Basic physical and chemical properties: from white to cream color powder.

Fortum powder Pharmacotherapeutic group
Antibacterial agent for systemic use. Cephalosporins of the third generation. ATX code J01D D02.

Pharmacological properties

Pharmacodynamics.

Ceftazidime is a bactericidal cephalosporin antibiotic whose mechanism of action is associated with impaired bacterial cell wall synthesis.

Acquired antibiotic resistance varies from region to region and may change over time, and may differ significantly for individual strains. It is desirable to use local data on antibiotic susceptibility and data on the spread of microorganisms that produce beta-lactamases with an extended spectrum of action, especially in the treatment of severe infections.

Sensitive microorganisms

Gram-positive aerobes: Streptococcus pyogenes, Streptococcus agalactiae.

Gram-negative aerobes: Citrobacter koseri, Haemophilus influenzae, Moraxella catarrhalis, Neisseria meningitides, Proteus mirabilis, Proteus spp., Providencia spp., Pasteurella multocida

Strains with possible acquired resistance

Gram-negative aerobes: Acinetobacter baumannii, Burkholderia cepacia, Citrobacter freundii, Enterobacter aerogenes, Enterobacter cloacae, Escherichia coli, Klebsiella pneumoniae, Klebsiella spp., Pseudomonas aeruginosa, Serratia slaganii, Morga.

Interaction with other medicinal products and other forms of interaction
Concomitant use of high doses of the drug with nephrotoxic drugs may adversely affect renal function (see section “Peculiarities of use”).

Chloramphenicol is an antagonist of ceftazidime and other cephalosporins in vitro. The clinical significance of this phenomenon is unknown, however, if concomitant use of Fortum with chloramphenicol is suggested, the possibility of antagonism should be considered.

Like other antibiotics, Fortum can affect the intestinal flora, reducing estrogen reabsorption and reducing the effectiveness of combined oral contraceptives.

Ceftazidime does not affect the results of the determination of glucosuria by enzymatic methods, but a small effect on the results of the analysis can be observed when using copper reduction methods (Benedict, Fehling, Clinitest).

Ceftazidime does not affect the alkaline-picratic method of creatinine determination.