Ftalazol tablets 0.5 №10


Manufacturer: Ukraine

Acute dysentery (shigellosis); chronic dysentery in the acute stage; colitis, enterocolitis, gastroenteritis; to prevent infectious complications during bowel surgery.



Ftalazol Composition
active substance: phthalylsulfathiazole;

1 tablet contains phthalazole (phthalylsulfathiazole) 500 mg;

excipients: potato starch, povidone, colloidal anhydrous silicon dioxide, talc, calcium stearate.

Ftalazol Dosage form.


Basic physical and chemical properties: tablets of white or white color with a slightly yellowish tinge, flat-cylindrical shape, with a line and a chamfer.

Pharmacotherapeutic group. Antimicrobial agents used for intestinal infections.

ATX code A07A B02.

Ftalazol Pharmacological properties


Sulfanilamide drug with a broad spectrum of action, active against gram-positive and gram-negative microorganisms – pathogens of intestinal infections. It has a bacteriostatic effect, the mechanism of which is due to a violation of the synthesis in microorganisms of their growth factors – folic and dehydrofolic acids, which are necessary for the synthesis of purines and pyrimidines.


The drug is slowly absorbed from the gastrointestinal tract, its main amount is retained in the intestinal lumen. In the small intestine, it breaks down to form sulfathiazole (norsulfazole), which has a high antimicrobial activity.

The created high concentration of sulfathiazole in the intestine, taking into account the specific bacteriostatic activity in relation to the intestinal flora, determines the effectiveness of phthalylsulfathiazole in intestinal infections.

Clinical characteristics.

Acute dysentery (shigellosis), chronic dysentery in the acute phase;
colitis, enterocolitis, gastroenteritis;
prevention of infectious complications during bowel surgery.
Individual hypersensitivity to phthalylsulfathiazole, sulfa drugs and / or other components of the drug;
Graves’ disease;
blood diseases;
acute hepatitis.