Primary therapy for local progressive or metastatic non-small cell lung cancer (for monotherapy or in combination with cisplastin). Locally progressive or metastatic pancreatic cancer. Inoperable or metastatic bladder cancer. Inoperable, locally recurrent or metastatic breast cancer that recurs after adjuvant / neoadjuvant chemotherapy (in combination with paclitaxel). In the absence of clinical contraindications, preliminary chemotherapy with anthracycline should be performed. Recurrent epithelial ovarian cancer, when relapses were observed more than 6 months after treatment with platinum drugs (in combination with carboplatin).