For primary plasma replacement in cases of blood loss and burns, ISO-and hypotonic dehydration due to indomitable vomiting, profuse diarrhea, intestinal obstruction, peritonitis; for partial compensation of the need for carbohydrates, including as part of complex therapy for patients with diabetes mellitus and other disorders of glucose utilization, subject to normal acid-base balance of the blood or when it shifts to the alkaline side.
Glicosteril F-5 Composition
active ingredients: sodium chloride, potassium chloride, calcium chloride dihydrate, magnesium chloride hexahydrate, fructose
100 ml of solution contain: sodium chloride – 0.8 g of potassium chloride – 0.0298 g of calcium chloride dihydrate – 0.0242 g of magnesium chloride hexahydrate – 0.0254 g of fructose – 5 g
ionic composition per 1000 ml of solution: Na + – 136.89 mmol K + – 4 mmol Ca ++ – 1.65 mmol
Mg ++ – 1.25 mmol Cl – 146.69 mmol
excipient: water for injection.
Glicosteril F-5 Dosage form.
Solution for infusion.
Basic physical and chemical properties:
transparent colorless or slightly yellowish liquid theoretical osmolarity – 568 mosmol / l pH 3.0 – 6.0.
Glicosteril F-5 Pharmacotherapeutic group.
Solutions for the correction of electrolyte imbalance. Electrolytes with carbohydrates. ATX code B05B B02.
Plasma-substituting isotonic saline solution containing a balanced composition of ions necessary for the body and fructose. The drug compensates for the loss of fluid, electrolytes and partially – energy, restores the water-salt balance. Fructose stimulates the formation of glucose and glycogen in the liver, improves the flow of glucose into cells. The metabolism of fructose is carried out independently of insulin; when it is used, the level of glucose in the blood does not increase, which is important in the treatment of patients with diabetes mellitus. Fructose has a pronounced antiketogenic effect, has a slight diuretic effect, has a specific effect on protein metabolism, which is manifested in the preservation of amino acids due to their less use in gluconeogenesis.
For primary replacement of plasma in case of blood loss and burns, iso- and hypotonic dehydration due to uncontrollable vomiting, profuse diarrhea, intestinal obstruction, peritonitis to partially compensate for the need for carbohydrates, including as part of complex therapy in patients with diabetes mellitus and other disorders of glucose utilization, under the condition of normal acid-base balance of blood or its shift to the alkaline side.
Edema, hypervolemia, hypersensitivity to fructose and / or to other components of the drug, methanol intoxication, hyperlactatemia, hypertensive dehydration, metabolic acidosis.