Linex capsules (Lactobacillus acidophilus) №32 vial


It is prescribed for the correction of intestinal dysbiosis, as well as the prevention / treatment of diarrhea caused by viral / bacterial infections of the digestive tract (traveler’s diarrhea, rotavirus infection), as well as the use of antimicrobial drugs (antibiotics, synthetic antimicrobial agents).



Linex capsules composition
active substances: 1 capsule contains not less than 1.2 × 107 CFU of antibiotic-resistant lactic acid bacteria: not less than 4.5 × 106 CFU of Lactobacillus acidophilus (sp. L. gasseri), not less than 3.0 × 106 CFU of Bifidobacterium infantis, not less than 4 , 5 × 106 CFU Enterococcus faecium;
excipients: lactose monohydrate, potato starch, dextrin, magnesium stearate;
shell: gelatin, titanium dioxide (E 171).

Dosage form
Hard capsules.

Pharmacological properties
Linex capsules is a combined medicine containing three different types of lyophilized (dried in a special way) viable lactic acid bacteria living in different parts of the intestine. They are part of the normal intestinal microflora and also regulate and maintain the physiological (natural) balance of the intestinal flora. The preventive, therapeutic effect of these microorganisms is determined by different mechanisms. For example, they ferment lactose, shift the pH towards the acidic side. The acidic environment inhibits the growth of pathogenic and conditionally pathogenic bacteria, provides an optimal environment for the activation of digestive enzymes. In addition, lactic acid bacteria produce vitamins B1, B2, B6, B12, K, participate in the metabolism of bile pigments, bile acids, prevent the adhesion (adhesion) of pathogens to the intestinal wall, and produce bacteriocin substances (with antibacterial activity). Lactic acid bacteria stimulate humoral immunity as well as local immunity in the intestine.
Imbalance of lactic acid bacteria occurs for various reasons (viral / bacterial infections, the use of broad-range antibiotics, chemotherapy drugs, travel, irradiation of the pelvic organs, abdominal cavity). In newborns, a delay in the normal formation of intestinal microflora is possible. All this leads to indigestion, accompanied by flatulence (bloating), diarrhea (loose stools) or constipation.
The use of Linex capsules helps to maintain the normal state of the intestinal microflora, restore the disturbed balance of intestinal microorganisms.
After oral (oral) administration, lactic acid microorganisms have a local effect in the intestine. They are not absorbed, do not enter the bloodstream.
According to the results of preclinical studies, including generally accepted studies of drug safety, its toxicity, carcinogenicity (ability to cause cancer), teratogenicity (adverse effects on the fetus), genotoxicity (harmful effects on cellular genetic material), the drug is safe.

It is prescribed for the correction of intestinal dysbiosis, as well as the prevention / treatment of diarrhea caused by viral / bacterial infections of the digestive tract (traveler’s diarrhea, rotavirus infection), as well as the use of antimicrobial drugs (antibiotics, synthetic antimicrobial agents).

You can not prescribe Linex capsules with increased reactivity (allergies) to the drug components.
For children under six years of age, diarrhea treatment can only be carried out under medical supervision.
1 capsule contains 98.28 mg of lactose, so it should not be used by people with hereditary / acquired galactose intolerance, lactase enzyme deficiency, glucose-galactose malabsorption syndrome (impaired absorption).
The capsules contain residues of milk protein – this can provoke an allergic reaction.
Before using this medication, you must consult a doctor in such cases:

  • if the duration of diarrhea (diarrhea)> 2 days;
  • at body temperature> 38 ° C;
  • if there is blood, mucus in the feces;
  • with diarrhea accompanied by severe abdominal pain;
  • with intense diarrhea with dehydration, weight loss;
  • in the presence of chronic diseases (diabetes mellitus, cardiovascular diseases) or immunodeficiency (for example, AIDS).

Apply in pediatric practice.

Application during pregnancy and lactation
There are no reports of undesirable effects when using the drug in pregnant women, nursing mothers. However, in the case of severe diarrhea, precautions should be taken to avoid the development of dehydration and electrolyte deficiency, as well as other side effects that may be dangerous to the fetus or pregnant women. During pregnancy or lactation, diarrhea should only be treated under medical supervision. It is not recommended to use the drug in question during this period, since there is insufficient data regarding its safety.

Method of application and dosage

  • Infants and children under 2 years: 1 capsule 3 times a day.
  • Children aged 2 to 12 years: 1-2 capsules 3 times a day.
  • Adults and children over 12 years of age: 2 capsules 3 times a day.
  • Children under 6 years of age should be treated for diarrhea under medical supervision.

If the child cannot swallow the whole capsule, it is necessary to open it and mix the contents of the capsule with a teaspoon of liquid (tea, juice, sweetened water). The resulting mixture is not subject to storage.
To prevent the adverse effect of gastric juice on lactic acid bacteria, the drug is recommended to be taken with food. Linex capsules should not be taken with alcohol or hot drinks.
The drug should be taken until the patient’s condition improves.
The duration of treatment depends on the cause of the disease and the individual characteristics of the organism.
If diarrhea does not stop within 2 days, despite taking the drug, you need to see a doctor.
With diarrhea, special attention should be paid to replenish fluid and electrolytes.

There are no reports of overdose cases. This medicine does not pose a threat to human life or health, even in high doses.

Side effects
Possible hypersensitivity reactions, manifested by redness of the skin, itching, urticaria rashes (urticaria), skin irritation, allergic rhinitis, shortness of breath, Quincke’s edema (rapidly developing swelling of the face or part of it, eyes, lips, larynx with respiratory failure), anaphylactic shock ( severe itching of the skin, quickly spreading over the skin, a sharp drop in blood pressure, vomiting, loose stools, swelling of the larynx, noisy and difficult breathing, pallor / cyanosis of the skin, a sharp narrowing of the bronchi and larynx, which leads to acute difficulty in breathing, loss of consciousness, work disorder vital organs).

Storage conditions and periods
Store the bottle tightly closed at 15–25 ° C. After the first opening of the bottle, the maximum shelf life is 4 months.