Lisinopril-Teva-10 mg tablets 10 mg. №60

$25.00

Lisinopril-Teva-10 mg is used:

  • with heart failure (as symptomatic treatment);
  • in acute myocardial infarction (for short-term treatment of hemodynamically stable patients);
  • with complications from the kidneys (nephropathy) with diabetes mellitus.
Category:

Description

Lisinopril-Teva-10 mg composition
active substance: lisinopril;
1 tablet contains lisinopril 10 mg in the form of lisinopril dihydrate;
Excipients: mannitol (E 421), calcium hydrogen phosphate, pregelatinized corn starch, croscarmellose sodium, magnesium stearate, iron oxide yellow (E 172), iron oxide red (E 172).

Dosage form
Tablets.

Pharmacological properties
It is an antihypertensive (blood pressure lowering) drug that works by inhibiting the renin-angiotensin-aldosterone system. Suppresses the influence of the angiotensin-converting enzyme, which catalyzes the conversion of angiotensin-I into the vasoconstrictor peptide angiotensin-II, preventing its stimulating effect on the secretion of aldosterone by the adrenal glands.

Indications
Lisinopril-Teva-10 mg is used:

  • with heart failure (as symptomatic treatment);
  • in acute myocardial infarction (for short-term treatment of hemodynamically stable patients);
  • with complications from the kidneys (nephropathy) with diabetes mellitus.

Contraindications
Do not use Lisinopril-Teva-10 mg:

  • with intolerance to the components;
  • with intolerance to other ACE inhibitors;
  • with a history of angioedema;
  • with mitral / aortic stenosis or hypertrophic cardiomyopathy with severe hemodynamic disorders;
  • with bilateral stenosis of the renal artery (aa. renalis dextra et sinistra) or stenosis of the renal artery (a. renalis) of a single kidney;
  • with cardiogenic shock;
  • in acute myocardial infarction with unstable hemodynamics;
  • with a creatinine level in the blood of 220 μmol / l or more;
  • during pregnancy / lactation.

Children
Efficacy and safety of the drug in children have not been established, so it should not be used in pediatric practice.

Application during pregnancy and lactation
This medicine is contraindicated in pregnant women, as well as in women planning pregnancy. Bo II-III trimesters of pregnancy, the drug has fetotoxicity (causes a decrease in renal function, delayed ossification of the skull, oligohydramnios), neonatal toxicity (causes kidney failure, hyperkalemia, arterial hypotension). Not used in nursing mothers.

Method of administration and dosage
Lisinopril-Teva-10 mg is administered orally (inside).
The dose prescribed by the doctor should be taken once a day, every day at the same time, regardless of food.
The standard initial dose is 2.5–10 mg, the therapeutic dose is 20 mg, and the maximum dose is 80 mg.

Overdose
Symptoms: drop in blood pressure, vascular insufficiency, renal failure, electrolyte imbalance, hyperventilation, palpitations, tachycardia / bradycardia, dizziness, cough, anxiety.
It is necessary to take measures to remove the drug from the body (artificially induce vomiting or rinse the stomach, apply sorbents, sodium sulfate). In case of an overdose, the introduction of saline, angiotensin II and / or catecholamines is recommended.
May be cleared by hemodialysis, but metal sulfonate polyacrylonitrile high-throughput membranes (AN69) should be avoided.

Side effects
Possible lymphadenopathy, bone marrow suppression (anemia, thrombocytopenia, leukopenia, agranulocytosis, neutropenia), autoimmune diseases, hemolytic anemia, hypoglycemia, headache, paresthesia, mood changes, vertigo, taste disorders, sleep disturbance, impaired sense of smell, confusion, depression imbalance, syncope, disorientation, tinnitus, decreased visual acuity, arterial hypotension, fainting, orthostatic effects, myocardial infarction, stroke, palpitations, Raynaud’s syndrome, tachycardia, AV block II, dry cough, bronchospasm, rhinitis, bronchitis, sinusitis , eosinophilic pneumonia / alveolitis, glossitis, diarrhea, abdominal pain, dry mouth, nausea, pancreatitis, hepatocellular / cholestatic hepatitis, liver failure, rash, itching of the skin, alopecia, psoriasis, angioedema, urticaria, dermatitis, urticaria , pseudolymphoma of the skin, polymorphic erythema, fever, arthralgia / arthritis, vasculitis, myalgia, positive anal from ANA, increased ESR, photosensitivity, renal dysfunction, uremia, impotence, acute renal failure, oliguria / anuria, gynecomastia, fatigue, increased levels of urea / creatinine, liver enzymes, bilirubin in the blood, proteinuria, hyperkalemia, hyponatremia.

Storage conditions and periods
Store Lisinopril-Teva-10 mg for no more than 4 years under normal conditions.