Longocaine Chevi solution for injections 5 mg/ml. 5 ml. vial №5


Shown Longocaine Chevi for subarochnoid (intrathecal) spinal anesthesia.



Longocaine Chevi composition
active substance: bupivacaine;
1 ml of solution contains bupivacaine hydrochloride anhydrous 5 mg;
Excipients: glucose monohydrate, water for injections.

Dosage form
Solution for injection.

Pharmacological properties
It is a local anesthetic. It is an anesthetic of the acid amide type with an average latency period. The effect of the drug is growing rapidly and is expressed by prolonged circulating blockade of sensory, motor and autonomic nerve fibers, the conducting system of the heart. It is assumed that the action of the drug is associated with inhibition of the permeability of the sodium channels of the membranes.

Shown Longocaine Chevi for subarochnoid (intrathecal) spinal anesthesia.

The medicine is not used:

  • with intolerance to the components;
  • with allergy to local anesthetics of the acid-amide type;
  • with active diseases of the nervous system (intracranial hemorrhage, meningitis, poliomyelitis, subacute combined degeneration of the spinal cord against the background of pernicious anemia, brain / spinal cord tumors);
  • with stenosis of the spinal canal;
  • with diseases of the spinal canal in the active stage (spondylitis, tuberculosis, tumors);
  • with recent spinal injuries;
  • with septicemia;
  • with a purulent infection of the skin in the place (or near) of the puncture of the spine;
  • with cardiogenic, hypovolemic shock;
  • in violation of blood clotting, treatment with anticoagulants.

This drug is used in pediatric practice for children from birth.

Application during pregnancy and lactation
Longocaine Chevi is not used during these periods.

Method of administration and dosage
The dose is selected individually in each case, taking into account the clinical situation. Apply the minimum dose that provides the necessary pain relief.
The drug has a fast onset, long duration of action.
The duration of anesthesia in the T10-T12 segments is 2-3 hours.
The drug causes moderate relaxation of the muscles of the lower extremities (2-2.5 hours), abdominal muscles (45-60 minutes). The duration of the blockade of muscle activity does not exceed the duration of pain relief.
For intrathecal administration in surgery, 2-4 ml (10-20 mg) are used.

Symptoms: tinnitus, involuntary eye movements, seizures, tingling, itching, numbness, tinnitus, anxiety, metallic taste in the mouth, tremors, muscle twitching, fear, vomiting, disorientation, speech impairment, vomiting, dizziness, confusion , drowsiness, tremors, seizures (tonic-clonic), motor activity, rapid breathing, dilated pupils, sphincter paralysis, stupor, decreased muscle tone, intermittent breathing, coma, respiratory arrest, death, palpitations, high blood pressure, rapid breathing, tachycardia , arrhythmia, hypoxia, pallor, cyanosis, drop in blood pressure, bradycardia, acute heart failure, asystole, ventricular fibrillation.
In case of an overdose, it is necessary to immediately stop the administration, ensure airway patency, and additional oxygen supply.
Therapeutic measures include control of hemodynamics, pupil width, symptomatic treatment.

Side effects
A feeling of “lightness in the head”, numbness of the tongue, dizziness, tinnitus, paralysis of the limbs, visual disturbances, convulsions, urinary retention, tremors, loss of consciousness, decreased cardiac output, respiratory arrest, blockade, ventricular arrhythmia (incl. ventricular paroxysmal tachycardia, asystole, ventricular fibrillation), bradycardia.

Storage conditions and periods
Store Longocaine Chevi at temperatures up to +25 ° C for no more than two years.
It is forbidden to use after the expiration date indicated on the package.
Parents are obliged to ensure the safety of children, excluding the possibility of their access to medicine.