Loratadine-Akrikhin syrup 5 mg/5 ml. 100 ml. vial


Symptomatic treatment of allergic rhinitis and chronic idiopathic urticaria.



Loratadine-Akrikhin composition
active substance: loratadine;
1 ml of syrup contains loratadine 1 mg;
excipients: propylene glycol; sodium saccharin; glycerin; citric acid, monohydrate; sorbitol solution that does not crystallize (contains E 420); methyl parahydroxybenzoate (E 218); propyl parahydroxybenzoate (E 216); flavoring “Wild strawberries” (contains: ponso 4 R (E 124), azorubin E 122)); purified water.

Dosage form

Pharmacological properties
Loratadine is a tricyclic antihistamine with selective activity against peripheral H1-receptors.
When used in the recommended dose has no clinically significant sedative and anticholinergic effects. During long-term treatment, no clinically significant changes in vital signs, laboratory tests, physical examination data, or electrocardiograms were detected. Loratadine has no significant effect on the activity of H2-histamine receptors. It does not block the uptake of norepinephrine and does not actually affect the cardiovascular system or the activity of the pacemaker.
After a single dose of the drug (10 mg) on ​​the basis of skin tests for histamine, it was found that the antihistaminic effect is clinically noticeable after 1-3 hours, reaches a peak in the range from 8 to 12 hours after onset of action and lasts 24 hours. There was no development of resistance when taking the drug for 28 days.

Symptomatic treatment of allergic rhinitis and chronic idiopathic urticaria.

Hypersensitivity to loratadine or to other components of the drug.

Efficacy and safety of the drug in children under 2 years of age have not been established.

Use during pregnancy or breastfeeding
There are very few data on the use of loratadine in pregnant women. As a precautionary measure, it is advisable to avoid the use of Loratadine-Akrikhin during pregnancy.
Physicochemical data indicate excretion of loratadine / metabolites in breast milk. As a risk to the infant cannot be ruled out, Loratadine-Akrikhin should not be used during breast-feeding.

Method of application and dosage
Apply orally. The Loratadine-Akrikhin can be used regardless of food intake.

  • Adults and children over 12 years of age should take 10 ml of syrup (10 mg of loratadine) once a day.
  • Doses for children aged 2 to 12 years depend on their body weight.
  • Children weighing more than 30 kg – 10 ml of syrup (10 mg of loratadine) 1 time per day.
  • Children weighing up to 30 kg – 5 ml of syrup (5 mg loratadine) 1 time per day.

In case of overdose, anticholinergic symptoms were noted: drowsiness, tachycardia and headache. In case of overdose, symptomatic and supportive treatment for the required period of time is recommended. Standard measures to remove the drug that is not absorbed from the stomach are recommended: gastric lavage, use of crushed activated charcoal with water.
Loratadine is not removed by hemodialysis, nor is it known whether loratadine is removed by peritoneal dialysis.
After emergency care, the patient should remain under medical supervision.

Side effects

  • Immune system: anaphylaxis, including angioedema;
  • Nervous system: dizziness, convulsions;
  • Cardiovascular system: tachycardia, palpitations;
  • Gastrointestinal tract: nausea, dry mouth, gastritis;
  • Hepatobiliary system: liver dysfunction;
  • Skin and subcutaneous tissue: rash, alopecia.

Expiration date
3 years.

Storage conditions
Store at a temperature not exceeding 25 ° C out of reach of children.