Symptomatic treatment of pathological conditions accompanied by memory impairment, cognitive disorders, with the exception of diagnosed dementia (dementia); treatment of cortical myoclonia: as a monopreparation or as part of complex therapy.
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Lucetam solution compositiom
active substance: piracetam;
1 ml of solution contains 200 mg of piracetam;
Excipients: sodium acetate trihydrate, glacial acetic acid, water for injections.
Solution for injection.
The active ingredient in Lucetam solution is piracetam, a cyclic derivative of gamma-aminobutyric acid. Piracetam is a nootropic drug that acts on the brain, improving cognitive functions such as learning ability, memory, attention, and mental performance in healthy people and patients with cognitive impairments. These effects are not related to sedation or stimulants. The effects of piracetam are associated with the stimulation of nucleotide metabolism in neurons, increased glucose levels and oxygen utilization in the brain, as well as enhanced cholinergic and dopaminergic mechanisms of excitation transmission in nervous tissue. Piracetam has the property of dose-dependent binding to the phospholipid double layer of cell membranes, and it restores their structure, thus increasing fluidity and improving membrane function.
Lucetam solution is used in therapy:
- consequences of ischemic strokes, which are accompanied by speech impairment, as well as motor and mental activity;
- psychoorganic syndromes, accompanied by dizziness, decreased memory, behavioral disorders, emotional lability, decreased concentration of attention, unsteady gait;
- senile dementia of the Alzheimer’s type and Alzheimer’s disease;
- dizziness and disturbances in balance, with the exception of dizziness of mental origin;
- chronic alcoholism and disease-induced withdrawal and psychoorganic syndromes;
- cortical myoclonus;
- low learning ability in children, especially when receiving specific skills in counting, reading, writing, which cannot be explained by inadequate teaching, mental retardation or family environment.
In addition, the appointment of Lucetam is indicated in the recovery period after injuries and intoxication of the brain.
Lucetam is not prescribed for patients who have had a hemorrhagic stroke, with renal failure, hypersensitivity to the active and auxiliary substances of the drug or pyrrolidone derivatives. It is unacceptable to use the drug in the treatment of nursing and pregnant women.
Application during pregnancy and lactation
Due to the fact that there have been no controlled studies regarding the safety of using this drug in the treatment of pregnant women, its appointment to this category of patients is unacceptable.
Piracetam is able to penetrate the placental barrier and be excreted in breast milk, therefore, when prescribing Lucetam to nursing patients, patients are recommended to refuse lactation.
Method of application and dosage
The drug in the form of an injectable solution should be used in acute cases or when it is impossible to use oral forms of piracetam. The drug is administered either intravenously (administered slowly, over several minutes), or as an infusion (used for 24 hours continuously).
The drug should be used in adult patients.
Treatment of conditions accompanied by memory impairment, cognitive disorders.
The initial daily dose is 4.8 g during the first week of treatment. Usually the dose is divided into 2-3 injections. The maintenance dose is 2.4 g per day. In the future, it is possible to gradually reduce the dose by 1.2 g per day.
Due to the fact that the active substance Lucetam piracetam does not have a toxic effect even in high doses, only isolated cases of drug overdose have been officially registered. When taking high doses of Lucetam for a long time, patients develop dyspeptic disorders, abdominal pain and diarrhea.
To improve the patient’s condition, he undergoes induction of vomiting, gastric lavage and the necessary symptomatic treatment is prescribed.
When taking Lucetam, some patients experience irritability, depression, headaches, drowsiness, insomnia, anxiety, dizziness, imbalance, exacerbation of epilepsy, hallucinations, increased libido, confusion, changes in blood pressure, dyspeptic disorders, epigastric pain, weight gain, etc. allergic reactions.
Storage conditions and periods
The drug should be stored in a dry and dark place, out of reach of small children. The shelf life is 5 years.