Vulvovaginal infections caused by pathogens sensitive to the drug (pathogens, Trichomonas, fungi, yeast, chlamydia, fungi of the genus Candida). Diseases of the genitourinary system (cystitis, urethritis, pyelonephritis, pyelitis). Intestinal amoebiasis and giardiasis.
Macmiror Complex composition
active substances: nifuratel, nystatin;
1 capsule contains: nifuratel 500 mg, nystatin 200,000 IU;
excipient: dimethicone (dimethylpolysiloxane AK 1000);
shell composition: gelatin, sodium ethyl parahydroxybenzoate (E 215), sodium propyl parahydroxybenzoate (E 217), glycerin, titanium dioxide (E 171), iron oxide yellow (E 172).
Vaginal capsules are soft.
Nifuratel, which is part of it, has the property of disrupting the respiration of cells of microorganisms, which, in combination with other characteristics, leads to their death. Its action extends to aerobic microorganisms and to the yeast fungus – candida (thrush).
Nystatin is an antifungal antibiotic. It has the ability to replace sterol structures located in the cell membrane of the fungus, which entails the loss of the protective functions of the cell membrane and its death.
After using the drug, vaginal dysbiosis (violation of normal microflora) does not develop, since it has low toxicity and high selectivity of antimicrobial activity.
Antimicrobial, fungicidal, antiprotozoal drug, used in the treatment of vaginal infections, in particular, urogenital trichomoniasis, vaginal candidiasis, bacterial infections of urogenital localization, local treatment of chlamydia.
Should not be used if the patient is allergic (hypersensitive) to nifuratel or nystatin.
The drug should not be used in children.
Application during pregnancy and lactation
There are no reliable confirmed data on the complete safety of using the pharmaceutical complex for pregnant women and their fetus. Also, there is no information about whether the drug passes into breast milk.
Method of administration and dosage
After the evening hygienic actions, before going to bed, insert 1 suppository Macmiror Complex deep into the vagina. The duration of treatment until complete recovery is 8 days. The treatment regimen, including its duration, can be changed by the attending physician, based on the individual characteristics of the patient, the course of the disease.
There is no medical record of overdose with this drug.
Patients usually tolerate this drug well. Occasionally, there were reactions of an allergic nature of local irritating effects, as well as skin allergic effects – urticaria, itching.
Storage conditions and periods
Macmiror Complex retains its beneficial properties for 3 years, subject to storage conditions – a temperature not exceeding 25 ° C.