Medihronal (glucose, glycine) granules 28 g. package №2


Alcohol intoxication, abstinence; to increase the effectiveness of other methods of therapy; prevention of intoxication; secondary prevention of alcoholism.



Medihronal composition:

  • package number 1:
    active substance: 1 package contains: glucose monohydrate 17.5 g;
    excipient: povidone;
  • package number 2:
    active ingredients: 1 package contains: glycine 7.0 g; sodium formate 3.5 g;
    excipient: povidone.

Dosage form

Pharmacological properties
This Medihronal drug belongs to a group of drugs that are used to treat alcohol dependence.
The drug consists of a combination of active ingredients, including glucose, glycine and sodium formate.
During therapy with Medichronal, the accumulation in the patient’s body of toxic metabolic products of consumed ethanol, including acetaldehyde, is reduced. The drug in question works as a detoxification drug, improves metabolic processes, synthesizes catecholamines, including norepinephrine, and also improves neuromediation, activates the cerebral cortex.
In addition, the drug generally improves well-being, in particular, the functioning of the liver, and helps to improve the quality of sleep. The effect of reducing the symptoms of ethanol poisoning, reducing the symptoms of alcohol withdrawal is noted half an hour after taking the first dose of the drug.

The specified pharmaceutical agent Medihronal is used for:

treatment of alcohol intoxication, the state of alcohol withdrawal;

prevention of the state of intoxication;

secondary prevention of alcohol dependence.

Medihronal is also used to improve the effectiveness of other treatments for alcohol dependence.

The drug in question is contraindicated for use in cases where the patient has severe hypersensitivity (allergy) to the main or to one of the auxiliary components.

Also, use is contraindicated for:

  • severe forms of diabetes mellitus;
  • arterial hypertension.

It should be borne in mind that glycine, which is part of the drug, helps to reduce the toxicity of anticonvulsant and antipsychotic substances, as well as antidepressants.
When used simultaneously with tranquilizers and hypnotics, it enhances their effect aimed at inhibiting the central nervous system.

It is not used in pediatric practice.

Application during pregnancy and lactation
The drug should not be used in the treatment of pregnant women. If there is a need for use in nursing mothers, then lactation should be temporarily suspended for the duration of treatment.

Method of administration and dosage
This Medihronal is taken orally after meals.
The contents of the first and second bags should be dissolved in 200 ml of warm water.
To improve the taste of the prepared solution, it can be dissolved in drinks without carbon dioxide – juice, compote, etc.
In order to relieve acute alcohol intoxication, on the first day of admission, take 1 or 2 times a day, the next 2-3 days – 1 time per day.
With complex treatment, it is used in three courses of 7 days with a break of 3 days. The dosage in this case is 1 dose 1 time per day for 7 consecutive days.
In order to prevent relapses of alcoholism, every month and a half a new course is carried out, three times for 7 days, with three-day breaks in treatment.
It is also possible to conduct short courses 1-3 times a year, which last 1-2 weeks.
To avoid immediate intoxication, take 1 dose of the drug for half an hour about the intended intake of alcohol.

Overdose has not been observed at the moment. In case of an overdose, one should be wary of the possible occurrence of disturbances in the functioning of the digestive tract, in the form of nausea, bloating, diarrhea and increased side effects.
In case of excessive ingestion, symptomatic treatment is recommended.

Side effects
All substances that are part of Medichronal-Darnitsa are natural metabolites. For this reason, side effects are extremely rare.
At the same time, in some cases it is possible:

  • nausea;
  • headache, irritability, decreased concentration;
  • allergic reactions in the form of allergic urticaria, rash, itching.

Storage conditions and periods
Shelf life – no more than 3 years from the date of issue indicated on the packaging by the manufacturer.
Storage temperature should not exceed 25 ° C.