Metizolon (methylprednisolone) cream 1 mg/g. 15 g. tube


Atopic dermatitis (neurodermatitis, endogenous eczema); real (true) eczema; simple contact dermatitis and allergic contact dermatitis; dyshydrotic eczema, children’s eczema, seborrheic dermatitis (and eczema), including on the scalp; numular eczema, dermatoses of the scalp of an inflammatory nature, accompanied by itching.



Metizolon composition
active substance: methylprednisolone;
1 g of the drug contains methylprednisolone aceponate micronized 1 mg;
Excipients: butylhydroxyanisole (E 320), isopropyl myristate, white soft paraffin, peach oil, glycerol monostearate, cetostearyl alcohol, polyethylene glycol stearate, edetate disodium, glycerin, benzyl alcohol, purified water.

Dosage form
Cream for external use.

Pharmacological properties
This drug Metizolon belongs to the group of antimicrobial and antiseptic substances based on corticosteroid components, intended for topical use in dermatology.
Methylprednisolone is a synthetic glucorticosteroid used to reduce inflammation by inhibiting the secretion and release of inflammatory mediators.
Promotes inhibition of the accumulation of cells (leukocytes, macrophages, etc.) in the inflamed area. Helps reduce capillary permeability.
It causes the restoration of adrenal function, increases protein catabolism, the content of glucose and lipid acids in the blood, affects the metabolism of amino acids.
Its use also reduces the likelihood of scar tissue formation.

This drug Metizolon is used to treat:

  • psoriasis;
  • atopic dermatitis;
  • eczema of various forms;
  • dyshidrosis;
  • seborrheic dermatitis;
  • ichthyosis;
  • ichthyosis dermatoses, accompanied by dryness and hyperkeratosis.

It is especially recommended to use if the disease is characterized by increased exudation (liquid discharge), or if the treated area has hair, since the composition of the drug does not interfere with the release of exudate.

You should not use the specified drug if the patient has had a previous hypersensitivity (allergy) with respect to one of the components that are part of the drug – both main and auxiliary.
Contraindicated in:

  • Cushing’s syndrome;
  • wounds and ulcers;
  • fungal skin lesions;
  • tuberculosis of the skin;
  • cutaneous syphilis;
  • skin tumors, acne;
  • simple and herpes zoster;
  • dermatoses with increased exudation;
  • during the vaccination period.

In pediatrics, it can be used from 4 months of age.

Application during pregnancy and lactation
Treatment of pregnant women in the first trimester is carried out with great caution, only according to indications, since there is a risk of impaired fetal growth or complications from the adrenal glands.
In the II and III trimester, as well as during breastfeeding, treatment with this drug is allowed, since it enters the bloodstream in doses that are safe for the mother and child.

Method of administration and dosage
Apply Metizolon cream in a thin layer.
It is permissible to apply the drug once a day.
The duration of treatment is 12 weeks, in children – no more than 4 weeks.

An overdose of this drug can cause increased side effects, the occurrence of atrophoderma.
Edema, itching, rash may occur.
In general, symptomatic treatment is recommended. Overdose symptoms usually disappear several weeks after the end of treatment.

Side effects
Usually the drug is well tolerated. Side effects can occur only with prolonged use of the drug.
In this case, you may observe:

  • convulsions, increased intracranial pressure;
  • Cushing’s syndrome;
  • anaphylactic reactions, hypersensitivity reactions;
  • itching, hyperemia, swelling and skin rash;
  • allergic dermatitis, allergic urticaria, skin irritation;
  • hypertrichosis (increased hair growth in the area of ​​application of the drug);
  • dry skin, burning sensation, tingling sensation, skin irritation, steroid acne, purpura, telangiectasia.

Long-term use can cause the drug to enter the bloodstream, and cause systemic reactions in the body in the form of secondary skin infections, atrophy of skin areas, hypertrichosis, hypercortisolism.

Storage conditions and periods
This medicinal product Metizolon is able to retain its medicinal properties for 2 years, from the date of manufacture indicated on the package.
Storage is carried out in a dry place, away from sunlight.
Storage temperature should not exceed 25 ° C.