Long-term maintenance therapy for chronic forms of schizophrenia. Prevention of exacerbations of schizophrenia. Contraindication. Hypersensitivity to fluphenazine or any excipients of the drug. Obvious or suspected subcortical cerebral disorders. Serious disorders of consciousness, severe cerebral atherosclerosis, pheochromocytoma, severe renal or liver failure, heart failure, hypersensitivity to other phenothiazines. Acute intoxication with Central nervous system inhibitors (alcohol, antidepressants, neuroleptics, sedatives, tranquilizers, sleeping pills, and drugs). Children under 12 years of age.