Naftideril (naftifine hydrochloride) solution 1% 10 ml. vial


Local treatment of fungal infections caused by naftifin-sensitive pathogens: fungal infections of the skin and skin folds; interdigital mycoses; fungal nail infections (onychomycosis); skin candidiasis; pityriasis versicolor; inflammatory dermatomycosis, with or without itching; mycosis of the external auditory canal.



Naftideril composition
Main active ingredient: naftifine hydrochloride.
Excipients included in the preparation: propylene glycol, ethanol, purified water.

Release form
It is produced in the form of a solution for external (cutaneous) use, in 10 ml vials. 1 ml of the drug contains 10 mg of naftifine hydrochloride.

Pharmacological properties
Naftideril belongs to a group of drugs used for the treatment of fungal skin diseases, used topically, in dermatological practice.
The main active component of the drug is naftifine hydrochloride, belongs to the allylamine class. This substance has a strong antimycotic effect when applied topically.
Possesses fungicidal properties against fungi of various types – trichophytons, epidermophytos, microsporums, yeast of the genus Candida, mold aspergillus, and others.
It can exhibit both fungicidal and fungistatic effects against microorganisms of the yeast group, and it depends on the fungal strain.
Naftifine also exhibits an antibacterial effect against pathological microorganisms of both gram-positive and gram-negative groups, which can cause infection with bacteria along with mycotic diseases.
The drug also has an anti-inflammatory effect, helping to accelerate the elimination of inflammation and the associated itching.

Naftideril is used for topical, topical treatment of mycosis infections, in particular:

  • fungal infections of the skin and skin folds, cutaneous candidiasis;
  • interdigital mycosis;
  • fungal infections of the nails (onychomycosis);
  • pityriasis lichen;
  • inflammatory dermatomycosis, with or without itching;
  • mycosis of the external auditory canal.

The drug in question is contraindicated for use in cases where the patient has severe hypersensitivity (allergy) to the main or to one of the auxiliary components.
It is contraindicated to apply to open wound surfaces, damaged skin, mucous membranes (including eyes).

It is not used in pediatrics.

Application during pregnancy and lactation
This drug is undesirable for the treatment of pregnant women – only with serious indications for this.
If it is necessary to take the drug during breastfeeding, lactation is suspended.

Method of administration and dosage
Naftideril is for topical, external use only.
Apply to the surface affected by the fungus 1 time per day (with onychomycosis – 2 times a day, cutting off the nails as much as possible).
You should first clean and dry the skin.
Recommended duration of treatment:

  • dermatosis – 2-4 weeks;
  • candidiasis – 4 weeks;
  • infections and mycoses of nails – up to 6 months;
  • mycoses of the ears – 2 weeks, laying cotton turundas, for 5-8 minutes, 2 times a day.

To prevent relapse, treatment is continued for another 2 weeks after the symptoms of the disease disappear.

Overdose cases have not been recorded at the moment. It is theoretically possible to increase side effects.
In case of overdose, treat the symptoms.

Side effects
The drug is usually well tolerated. Side effects may occur in the form of:

  • hypersensitivity reactions, including angioedema;
  • rash, allergic urticaria, itching;
  • redness, burning, erythema;
  • local irritation;
  • itching.

If unspecified side effects occur, you should consult your doctor to change or adjust the treatment regimen.

Storage conditions and periods
Expiration date – up to 3 years from the production date indicated on the package.
The storage temperature should not exceed 30 ° C.