Neuromax (vitamin B1, B6) coated tablets №60


Neurological diseases of various origins: neuritis, neuralgia, polyneuropathy (diabetic, alcoholic), radicular syndrome, retrobulbar neuritis, facial nerve damage.



Neuromax composition
active substances: pyridoxine hydrochloride, benfotiamine;
1 tablet contains pyridoxine hydrochloride 100 mg, benfotiamine 100 mg;
Excipients: colloidal anhydrous silica, microcrystalline cellulose, talc, povidone, calcium stearate, corn starch, dry mixture “Opadry II white” containing titanium dioxide (E 171), talc, polyethylene glycol, polyvinyl alcohol.

Dosage form
Film-coated tablets.

Pharmacological properties
This is a combination of B vitamins. It is used in the complex therapy of neurological diseases. Vitamin B1 (an analogue of thiamine) plays an important role in the reactions of fat, protein, carbohydrate metabolism. He actively participates in the processes of conducting nervous excitement. Vitamin B6 (pyridoxine) is necessary for the body for the normal functioning of the nervous system. Vitamin B12 (cyanocobalamin) is required for normal hematopoiesis (hematopoiesis), maturation of red blood cells (erythrocytes), is involved in many biochemical reactions that ensure the vital activity of the human body.

Neuromax is used in the complex treatment of neurological diseases:

  • plexitis;
  • polyneuropathy of various origins (including diabetic, alcoholic);
  • sciatica;
  • lumbago;
  • chronic / acute neuralgia;
  • neuritis;
  • trigeminal neuralgia;
  • paresis of the facial nerve;
  • radicular syndrome caused by degenerative lesions of the spine;
  • intercostal neuralgia.

Hypersensitivity to the components of the drug.
Vitamin B1 is contraindicated in allergic reactions.
Vitamin B6 is contraindicated in peptic ulcer of the stomach and duodenum in the acute stage (because it may increase the acidity of gastric juice).

Efficacy and safety of the drug in children have not been established, so it should not be prescribed to this age group of patients.

Use during pregnancy or breastfeeding
The drug contains 100 mg of vitamin B6, so it should not be used during pregnancy and breastfeeding.

Method of application and dosage
Apply Neuromax orally, drinking plenty of fluids.
The recommended dose is 1 tablet per day. In individual cases, the dose is increased and used 1 tablet 3 times a day.
The tablets should be taken whole with liquid after a meal.
The duration of treatment is determined by the doctor individually in each case. After the maximum period of treatment (4 weeks), a decision is made to adjust and reduce the dose of the drug.

In case of overdose, the symptoms of side effects of the drug increase.
Treatment: gastric lavage, use of activated charcoal. Therapy is symptomatic.
With chronic use in high doses may worsen the activity of liver enzymes, heart pain and hypercoagulation.
Thiamine has a wide therapeutic range. High doses (more than 10 g) of vitamin B1 have a ganglioblocking curare-like effect and suppress the conduction of nerve impulses.
Continuous use of vitamin B6 in doses exceeding 1 g per day for more than 2 months can lead to neurotoxic effects.
Prolonged use (more than 6-12 months) in doses of more than 50 mg of vitamin B6 daily can lead to peripheral sensory neuropathy.
With long-term use of vitamin B1 at a dose of more than 2 g per day was recorded neuropathy with ataxia and sensitivity disorders, cerebral convulsions with changes in the EEG, and in some cases – hypochromic anemia and seborrheic dermatitis.

Side effects:

  • From the digestive tract: nausea, vomiting, diarrhea, abdominal pain, increased acidity of gastric juice.
  • From the cardiovascular system: tachycardia.
  • From the immune system: hypersensitivity reactions, including anaphylactic shock; anaphylaxis; urticaria.
  • From the skin: skin rash, itching.
  • In very rare cases – a state of shock.
  • From the nervous system: long-term use (more than 6-12 months) in doses of more than 50 mg of vitamin B6 daily can lead to peripheral sensory neuropathy, nervous excitement, dizziness, headache.
  • From the endocrine system: inhibits the secretion of prolactin.

Expiration date
2 years.

Storage conditions
Store in the original package at a temperature not exceeding 25 ºC.
Keep out of reach of children.