Nicoflex (natural capsaicin, ethyl nicotinate) ointment 50 g.


Arthritis, osteoarthritis, myalgia, recovery period of tendovaginitis, spondyloarthritis-related neuralgia. The drug is also indicated for athletes during warm-up.



Nicoflex composition
active substances: natural capsaicin, ethylnicotinate, hydroxyethyl salicylate;
1 g of ointment contains: capsaicin natural 0.15 mg, ethylnicotinate 20.0 mg, hydroxyethyl salicylate 90.0 mg;
Excipients: propyl parahydroxybenzoate (E 216), methyl parahydroxybenzoate (E 218), lavender oil, ethanol 96%, sodium lauryl sulfate, mineral oil, cetostearyl alcohol, white soft paraffin, purified water.

Dosage form

Pharmacological properties
Nicoflex is a combined drug that has a local vasodilating, warming, as well as distracting, analgesic and anti-inflammatory effect. Contains substances that cause prolonged dilation of superficial vessels at the application site, increase the temperature of the skin, which causes a feeling of warmth.
Ethylnicotinate has a vasodilating effect, which is realized directly through the prostaglandin mechanism.
Capsaicin when applied topically has an analgesic effect due to the inhibition of substance P in peripheral nociceptive C-fibers and A-delta nerve fibers.
Capsaicin or 6-nonenamide, N – [(4-hydroxy-3-methoxyphenyl) methyl] -8-methyl, (6E) – is a highly selective agonist of vaniloid receptors type 1 with transient receptor potential (TRPV1). The primary effect of capsaicin is to activate the skin’s TRPV1-releasing nociceptors, which causes a burning sensation and erythema due to the activation of vasoactive neuropeptides.
Hydroxyethyl salicylate affects the structure of the epithelium, which facilitates the absorption of the components of the ointment, has anti-inflammatory effects, reduces muscle tension.

Arthritis, osteoarthritis, myalgia, recovery period of tendovaginitis, spondyloarthritis-related neuralgia. The drug is also indicated for athletes during warm-up.

Hypersensitivity (allergy) to any of the components of the drug;
active stage of any inflammatory process;
open wounds, eczema of the skin and other skin lesions, purulent skin diseases;
hypersensitivity to acetylsalicylic acid, ibuprofen or other nonsteroidal anti-inflammatory drugs;
bronchial asthma.

Due to the lack of data on the use of the drug in children, the use of ointments in this category of patients is contraindicated.

Use during pregnancy or breastfeeding
Apply the ointment during pregnancy or breastfeeding is contraindicated.

Method of application and dosage
For external use only!
On a clean and dry area of ​​skin to be treated, apply a thin layer of ointment. Nicoflex ointment should be applied only to the painful area.
In diseases of the muscles and joints in adults, the ointment is applied once a day for 3 days, then 2 times a day (morning and evening).
The duration of treatment is determined by the doctor individually.
To warm up the muscles in adult athletes, apply a strip of ointment 4-5 cm on the skin and rub with gentle massaging movements until the skin becomes slightly red.

Not observed.

Side effects
Most side effects were mild or moderate and gradually disappeared in about an hour.
From the skin and subcutaneous tissue: redness of the skin, a feeling of warmth in the area where the drug was used; slight burning and tingling in the area of ​​skin where the drug was used; swelling at the site of application; local inflammation of the skin; contact eczema; allergic reactions; angioneurotic edema.
If any adverse reactions occur, the drug should be discontinued and a doctor should be consulted.

Expiration date
2 years.

Storage conditions
Store Nicoflex at a temperature not exceeding 25 ° C out of reach of children.