Prevention and treatment of pellagra (avitaminosis PP); atherosclerosis; hypoacid gastritis; spasms of blood vessels (brain, kidneys, limbs); neuritis of the facial nerve; long-term non-healing wounds and ulcers of various localization and Genesis.
Nicotinic acid composition and form of release
Made in tablets. The active ingredient is nicotinic acid (50 mg).
Nicotinic Acid belongs to the group of peripheral vasodilators. The drug normalizes the content of triglycerides and lipoproteins in the blood, improves microcirculation, and eliminates vitamin PP deficiency. It has anticoagulant, detoxification and anti-pellagric action.
Nicotinic acid is used to treat PP avitaminosis (pellagra), atherosclerosis, Hartnap’s disease, angina pectoris, neuritis of the facial nerve, hypercoagulation, intoxication, diseases of the digestive tract and long-term non-healing wounds and ulcers.
In addition, the use of vitamin PP is indicated in the treatment of peripheral vascular spasm in case of obliterating endarteritis, migraine, Rhine’s disease and cerebrovascular accident arising on the background of ischemic stroke. Nicotinic acid is used in the treatment of hyperlipidemia, hypercholesterolemia, hypertriglyceridemia.
The drug is not prescribed to those who have been diagnosed with nicotinic acid intolerance.
With prolonged use, the drug can cause fatty degeneration of the liver. To prevent the development of complications during long-term treatment with a drug, patients should consume products containing methionine and other lipotropic substances.
It is used in pediatrics.
Application during pregnancy and lactation
In the therapy of pregnant and lactating women, it is possible to use Nicotinic acid only in small doses.
Method of administration and dosage
Nicotinic acid is administered orally. In the form of tablets, the drug is recommended to be used only after meals. For prophylactic purposes, adults take the drug at 0.015 or 0.025 g, children – 0.005 or 0.02 g per day.
When treating pellagra, adults take orally 0.1 g from 2 to 4 times a day. Children receive from 0.005 to 0.05 g of the drug 2 to 3 times a day.
As part of the complex treatment of other pathological conditions and diseases, nicotinic acid is prescribed for adults at 0.02 or 0.05 g, for children – 0.005 or 0.03 g from 2 to 3 times a day.
The drug in high doses causes short-term rush of blood to the upper body and head, as well as gastrointestinal upset. To stabilize the patient’s condition, symptomatic treatment is carried out.
When the drug is taken on an empty stomach, it can cause dizziness, facial flushing, rush of blood to the upper half of the body and a feeling of numbness in the limbs. Rapid administration may result in a sharp drop in blood pressure.
Storage conditions and periods
Nicotinic acid should be stored in a dry, protected from light and out of reach of children. Duration of storage of the medicinal product is 5 years.