Normagut (Saccharomyces boulardi) capsules №10


Prevention and treatment of colitis and diarrhea associated with taking antibiotics. Intestinal dysbiosis. Acute and chronic bacterial diarrhea. Acute viral diarrhea. Traveler’s diarrhea. Irritable bowel syndrome. Pseudomembranous colitis and diseases caused by Clostridium difficile. Diarrhea associated with long-term enteral nutrition.



Normagut composition
The main active ingredient of the drug is Saccharomyces boulardii dry yeast (lyophilized).
Excipients are: anhydrous lactose, magnesium stearate, gelatin, titanium dioxide, yellow iron oxide, copper complexes of chlorophyllins, purified water.
1 capsule contains 250 mg of Saccharomyces boulardii yeast, which includes 221.25 mg of yeast and 28.75 mg of lactose monohydrate.

Release form
Produced in capsules

Pharmacological properties
This drug Normagut belongs to the group of antidiarrheal microbial drugs.
Restores the normal intestinal microflora, producing a pronounced etiopathogenetic antidiarrheal effect.
Passing through the digestive tract, the bacteria Saccharomyces boulardii protects the normal intestinal microflora. Saccharomyces boulardii are genetically resistant to antibiotics, which allows them to be used simultaneously with antibacterial drugs in order to protect the normal microbiocenosis of the digestive tract.
The drug is able to inhibit the growth of microorganisms and fungi that can disrupt the intestinal microbiocenosis. It produces an antitoxic effect due to its ability to produce proteases and break down toxins.
Has an antisecretory effect, reducing the secretion of water and salts, due to the ability to reduce the formation of cAMP in enterocytes.
Strengthens nonspecific immune protection due to increased production of immunoglobulins and secretory components of immunoglobulins. Also has enzymatic activity and trophic effect.

This product Normagut is intended for the treatment of:

  • acute and chronic bacterial diarrhea;
  • acute viral diarrhea;
  • traveler’s diarrhea;
  • intestinal dysbiosis;
  • irritable bowel syndrome;
  • pseudomembranous colitis and Clostridium difficile diseases;
  • diarrhea associated with long-term enteral nutrition.

Also prescribed for the prevention and treatment of colitis and diarrhea associated with taking antibiotics.

Not applicable if the patient has hypersensitivity (allergy) to one of the components that make up the drug.
It is contraindicated for use in patients with a central venous catheter.

It is contraindicated to use for the treatment of children under 2 years of age.

Application during pregnancy and lactation
Not recommended for use in pregnant women.
During treatment, lactation (breastfeeding) should be suspended.

Method of administration and dosage
Normagut is taken orally with water. Children under 6 years of age can consume the contents of the capsule without swallowing it. To do this, you need to open the capsule and mix its contents with a small amount of non-hot water.
Recommended dosage:

  • children aged 2 – 12 years – 1 capsule 1-2 times a day;
  • adults and children over 12 years old – 1-2 capsules 1-2 times a day.

The duration of the course of treatment is determined by the doctor. Usually when:

  • acute diarrhea – 3-5 days;
  • dysbiosis, chronic diarrheal syndrome, irritable bowel syndrome – 10-14 days.

For the prevention and treatment of antibiotic-associated diarrhea and pseudomembranous colitis, this drug is used in combination with antibacterial drugs, 2 capsules 2 times a day, from the first day of taking antibiotics.
To prevent traveler’s diarrhea, start taking it 5 days before arriving in an exotic country, and then take 1 capsule per day (on an empty stomach) throughout your stay. The maximum admission period is 1 month.

An overdose can cause an increase in side effects in the form of allergic reactions, as well as dyspeptic reactions – nausea, vomiting, flatulence.
Treatment of symptoms, gastric lavage, and sorbent intake are recommended.

Side effects
Usually, this drug is well tolerated, and the side effects that appear are usually mild.
The gastrointestinal tract can react with temporary discomfort in the epigastric region, flatulence, which do not require discontinuation of the drug.
With individual drug intolerance, hypersensitivity reactions are possible in the form of:

  • skin rash, hives, itching;
  • local and generalized exanthema;
  • Quincke’s edema, shortness of breath, anaphylactic shock.

In rare cases, there is a risk of fungemia in patients with a central venous catheter.
If you experience any unusual side effects as a result of taking this drug, you should consult your doctor about possible changes in the treatment regimen.

Storage conditions and periods
The shelf life of the drug is no more than 2 years from the production date indicated on the package.
This medicinal product should be stored in a dry place out of the reach of children, at a temperature not exceeding 25 ° C.