Olatropil (piracetam, gamma-aminobutyric acid) capsules №30


Olatropil is prescribed for adults: in diseases of the nervous system for the treatment of vascular encephalopathy (atherosclerosis, hypertension); in chronic cerebrovascular insufficiency with impaired memory, concentration, speech, dizziness, headache; for the treatment of encephalopathies (alcoholic, post-stroke, post-traumatic); in the treatment of senile dementia (including Alzheimer’s disease); for the treatment of psychoorganic syndromes of various etiologies.

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Olatropil composition
The main active ingredients are piracetam and gamma-aminobutyric acid.
Excipients: microcrystalline cellulose, talc, titanium dioxide, gelatin.

Release form
Produced in capsule form, each containing 250 mg of piracetam and 125 mg of gamma-aminobutyric acid.

Pharmacological properties
This Olatropil drug belongs to the group of psychostimulating and nootropic drugs.
The main active ingredients are piracetam, which is a cyclic derivative of gamma-aminobutyric acid and, in fact, gamma-aminobutyric acid itself.
Piracetam is a nootropic drug that stimulates mental abilities, activates cognitive functions, improves memory and increases learning ability.
It has the property of increasing the brain’s resistance to harmful effects on the brain, including relatively excessive mental stress or hypoxia.
Such properties are due to the mechanisms of action on the central nervous system, in particular, the ability to change the rate at which excitation spreads in the brain. It is also able to enhance metabolic processes, improve microcirculation in the brain, without dilating the blood vessels.
Able to reduce the intensity and duration of vestibular nystagmus.
Gamma-aminobutyric acid – the main mediator of the processes of inhibition of the central nervous system, a derivative of aminalone, has a mild psychostimulant effect.

This drug Olatropil is used to treat:

  • diseases of the nervous system, incl. vascular encephalopathy (atherosclerosis, hypertension);
  • chronic cerebrovascular insufficiency with impaired memory, concentration, speech, dizziness, headache;
  • encephalopathy (alcoholic, post-stroke, post-traumatic);
  • senile dementia (including Alzheimer’s disease);
  • psychoorganic syndromes of various etiologies.

Not applicable if the patient has hypersensitivity (allergy) to one of the components of the drug.
Also, use is contraindicated for:

  • end stage renal failure;
  • acute disturbance of cerebral circulation (hemorrhagic stroke);
  • Chorea of ​​Huntington.

Not used in pediatrics.

Application during pregnancy and lactation
For the treatment of pregnant women, it is used with great caution, since there is no reliably established data on the safety of this drug for pregnant women and the fetus.
If there is a need to take this drug, then lactation (breastfeeding) should be suspended during treatment.

Method of administration and dosage
It is recommended to take Olatropil in an optimal dosage, 1 capsule 3-4 times a day.
The maximum daily dose is 6 capsules.
The therapeutic effect, as a rule, occurs within 2 weeks from the start of treatment.
The duration of the course of treatment is determined on an individual basis. The average duration of treatment is 1 to 2 months.
If necessary, the course can be repeated after 6-8 weeks.
Elderly patients and patients with renal insufficiency require dosage reduction.
No dosage adjustment is required for liver problems.

When taking excessive dosages (more than 75 grams per day), the patient may experience an increase in side effects.
It is necessary to wash the stomach, take sorbents, establish monitoring of the patient’s condition, and, if necessary, carry out a complex of standard supportive symptomatic therapy.
Hemodialysis is recommended.

Side effects
Therapy with this drug can cause side reactions in the form of:

  • hyperkinesia, drowsiness, ataxia, balance disorders, increased frequency of epileptic seizures, headache, insomnia, tremors;
  • increase in body weight;
  • nervousness, depression, increased excitability, anxiety, hallucinations;
  • hemorrhagic disorders;
  • hypersensitivity, anaphylactoid reactions;
  • vertigo;
  • abdominal pain, diarrhea, nausea, vomiting;
  • angioneurotic edema, dermatitis, rash, allergic urticaria, itching;
  • increased sexual activity;
  • asthenia.

When these symptoms appear, the daily dose is recommended to be reduced or interrupted for several days. As soon as the side effects disappear, you can return to treatment again by carefully administering the dosage of the drug.

Storage conditions and periods
The shelf life of the drug is no more than 4 years from the production date indicated on the package.
Store in a dry place out of the reach of children, at a temperature not exceeding 25 ° C.