This drug is used to treat constipation of various etiologies. In particular, it is used for: regulation of the physiological rhythm of the intestine with constipation; treatment of conditions requiring relief of bowel movements (hemorrhoids, conditions after operations on the large intestine and anorectal zone; treatment of portosystemic hepatic encephalopathy – treatment and prevention of hepatic coma and precoma.
The main active ingredient of the drug is lactulose.
1 ml of the drug accounts for 667 mg of lactulose in liquid form.
It is produced in the form of a syrup for oral administration. It goes on sale packaged in bottles with a volume of 250 ml of syrup, with a measuring cup.
This drug Portalak belongs to the group of osmotic laxatives used in gastroenterology.
The main active ingredient is lactulose, which has the property of being broken down in the intestine by intestinal bacteria. As a result of these processes, it turns into low molecular weight organic acids.
The latter cause a decrease in acidity in the colon, increasing the volume of its contents and exerting an osmotic effect. Due to the normalization of the consistency of feces, the peristalsis of the large intestine is stimulated, constipation is corrected, the physiological digestive rhythm and the rhythm of bowel emptying are restored.
Lactulose also acts as a prebiotic, increasing the number of beneficial gut bacteria, specifically bifidobacteria and lactobacilli. It also inhibits the growth of bacteria that may be pathogenic, such as Clostridium or E. coli. Thus, the balance of intestinal microflora is normalized.
This drug Portalak is used to treat constipation of various etiologies.
In particular, it is used for:
- regulation of the physiological rhythm of the intestine with constipation;
- treatment of conditions requiring relief of bowel movements (hemorrhoids, conditions after operations on the large intestine and anorectal zone;
- treatment of portosystemic hepatic encephalopathy – treatment and prevention of hepatic coma and precoma.
Do not apply if the patient has hypersensitivity (allergy).
Also, use is contraindicated in:
- intestinal obstruction;
- perforation of the digestive tract;
- the risk of perforation of the digestive tract.
Application during pregnancy and lactation
This drug can be used during pregnancy and during breastfeeding, since the systemic effect of lactulose on a pregnant woman is insignificant. Also, no consequences for the fetus are expected.
Method of administration and dosage
Portalak can be taken either diluted or undiluted, in 1 or 2 divided doses per day. A single dose of lactulose is swallowed immediately without holding it in the mouth.
The dose and regimen of the drug should be selected in accordance with the needs of the patient.
If the drug is prescribed to the patient once a day, the dose should always be taken at the same time of the day, for example, during breakfast. During therapy with laxatives, it is recommended to consume a sufficient amount of liquid (1.5-2 liters per day, which corresponds to 8-10 glasses).
- adults and children over 14 years old – the initial dose is from 15 to 45 ml, the maintenance dose (after 2-3 days, after the appearance of the clinical effect) is from 15 to 30 ml;
- children from 14 to 7 years old – initial dose – 15 ml, maintenance dose – from 10 to 15 ml;
- children from 1 to 6 years old – initial dose – 5 to 10 ml, maintenance dose – 5-100 ml;
- children from birth to 1 year old – dosage in the amount of 5 ml of lactulose.
With a hepatic coma or precoma, the initial dosage can be up to 30 ml.
Elderly patients, as well as patients suffering from renal or hepatic insufficiency, do not need to adjust the dosage.
When taking excessive dosages, the patient may experience:
- abdominal pain;
It is recommended to stop taking the drug or reduce the dosage, correct electrolyte imbalance in case of excessive fluid loss, which may be caused by diarrhea or vomiting.
Therapy with this drug can cause adverse reactions, especially at the beginning of treatment. Among them were observed:
- abdominal pain, diarrhea (if the recommended dosage is exceeded).
When using large therapeutic dosages used for a long time, electrolyte imbalance may occur (due to prolonged significant dilution of the stool, diarrhea). Most often, this effect is observed in patients with hepatic insufficiency and encephalopathy, which should be taken into account in the treatment process.
In case of any unusual side effects, you should consult your doctor to adjust the course of treatment.
Storage conditions and periods
The shelf life of the drug is no more than 3 years from the production date indicated on the package.
Store in a dry place out of the reach of children, at a temperature not exceeding 25 ° C.