Psoriasis; atopic dermatitis; various forms of eczema (including lichenization); dyshydrosis; seborrheic dermatitis; ichthyosis, ichthyoform dermatoses, accompanied by dryness and hyperkeratosis.
The main active ingredients are prednisolone, urea (carbamide).
Excipients: sodium edetate, propylene glycol, liquid paraffin, cetyl alcohol, stearyl alcohol, purified water, etc.
It is produced in the form of an ointment, in tubes with a volume of 15 grams, and 1 gram of the drug contains 5 mg of prednisolone and 100 mg of urea.
This drug belongs to the group of antimicrobial and antiseptic substances based on corticosteroid components, intended for topical use in dermatology.
Prednisolone is a synthetic corticosteroid used to reduce inflammation because it inhibits the secretion and release of inflammatory mediators.
Promotes inhibition of the accumulation of cells (leukocytes, macrophages, etc.) in the inflamed area. Helps reduce capillary permeability.
Promotes the restoration of adrenal function, increases protein catabolism, the content of glucose and lipid acids in the blood, affects the metabolism of amino acids.
Its use also reduces the likelihood of scar tissue formation.
Urea, which is also a part of the preparation, helps to regulate the water balance of the dermis, ensuring its elasticity, softening keratinized epithelial cells, and produces keratolytic, bacteriostatic and fungistatic effects. It has a local anesthetic effect. Reduces itching, aggravated by the use of prednisolone.
This drug Prednicarb is used to treat:
- atopic dermatitis;
- eczema of various forms;
- seborrheic dermatitis;
- ichthyosis dermatoses, accompanied by dryness and hyperkeratosis.
You should not use the specified drug if the patient has had a previous hypersensitivity (allergy) with respect to one of the components that are part of the drug – both main and auxiliary.
- Cushing’s syndrome;
- wounds and ulcers;
- fungal skin lesions;
- tuberculosis of the skin;
- cutaneous syphilis;
- skin tumors, acne;
- simple and herpes zoster;
- dermatoses with increased exudation;
- during the vaccination period.
In pediatrics, it can be used from 12 months of age.
Application during pregnancy and lactation
Treatment of pregnant women in the first trimester is carried out with great caution, only according to indications, since there is a risk of impaired fetal growth or complications from the adrenal glands.
In the II and III trimester, as well as during breastfeeding, treatment with this drug is allowed, since it enters the bloodstream in doses that are safe for the mother and child.
Method of administration and dosage
Apply Prednicarb ointment in a thin layer, then it is desirable to cover this area with an occlusive dressing.
It is permissible to apply the drug 1 to 3 times a day.
The duration of treatment is 1-2 weeks, in children – 5-7 days. Children are not recommended to apply occlusive dressings.
An overdose of this drug can cause increased side effects and edema.
Edema, itching, rash may occur. It is not recommended to abruptly interrupt treatment even in case of an overdose – the dose must be reduced gradually.
In general, symptomatic treatment is recommended. In case of significant overdose, administration of hydrocortisone is recommended.
The drug is usually well tolerated. Side effects can occur only with prolonged use of the drug.
In this case, you may observe:
- convulsions, increased intracranial pressure;
- Cushing’s syndrome;
- anaphylactic reactions, hypersensitivity reactions;
- itching, hyperemia, swelling and skin rash;
- allergic dermatitis, allergic urticaria, skin irritation;
- dry skin, burning sensation, tingling sensation, skin irritation, steroid acne, purpura, telangiectasia.
Prolonged use can cause the drug to enter the bloodstream and cause systemic reactions in the body in the form of secondary skin infections, atrophy of skin areas, hypertrichosis, hypercortisolism.
Storage conditions and periods
This medicinal product Prednicarb is able to retain its medicinal properties for 2 years, from the date of production indicated on the package.
Storage is carried out in a dry place, away from sunlight.
Storage temperature should not exceed 25 ° C.