Prilidji (dapoxetine) 30 mg. coated tablets 30 mg. №3


This drug Prilidji belongs to a group of drugs that are used to treat urological diseases, and is used to improve the sexual sphere in men.



Prilidji Ingredients
The main active ingredient of the drug is dapoxetine in the form of hydrochloride. The following are used as auxiliary ingredients: microcrystalline cellulose, lactose monohydrate, croscarmellose sodium, magnesium stearate, colloidal anhydrous silicon dioxide, etc.

Release form
It is produced in tablet form, in dosages of 30 mg of dapoxetine in one tablet.

Pharmacological properties
This drug Prilidji belongs to a group of drugs that are used to treat urological diseases, and is used to improve the sexual sphere in men.
The mechanism of its action is due to the qualities of its main active ingredient – dapoxetine.
The specified drug, as well as its main metabolites (chemicals that take part in metabolic processes in the cells of the body) – desmethyldapoxetine and didesmethyldapoxetine, are potent selective serotonin reuptake inhibitors.

The drug Prilidji is used in sexopathology to treat premature ejaculation in men.
This drug is recommended for use in patients who meet the following criteria:

  • insufficient control of the onset of ejaculation;
  • the latent time of intravaginal ejaculation is less than 2 minutes;
  • persistent or repeated ejaculation after minimal sexual stimulation before, during, and immediately after sexual penetration, which occurs earlier than the moment desired for the patient;
  • a pronounced state of stress or difficulties that arose in interpersonal relationships as a result of premature ejaculation.

The age at which safe and effective use of this drug is permissible is from 18 to 64 years.
It is used only to treat patients who have been diagnosed with premature ejaculation. Not intended for men who want to prolong sexual intercourse by delaying the onset of ejaculation.
There is no data on the safety of use in men who have not been diagnosed with premature ejaculation.
Before starting treatment with this drug, men with other forms of sexual dysfunction, including erectile dysfunction, should be examined by a doctor.
The mechanism of action of dapoxetine in premature ejaculation is associated with a delay in the neuronal reuptake of serotonin and further enhancement of the action of neurotransmitters on presynaptic and postsynaptic receptors.

Not applicable if the patient has hypersensitivity (allergy) to one of the components that make up the drug.
It is also contraindicated for use if the patient has:

  • heart failure;
  • cardiac conduction disorders (AV block, sick sinus syndrome);
  • coronary heart disease;
  • valvular heart disease;
  • hepatic and renal failure in moderate to severe degree;
  • history of syncope;
  • a history of mental disorders (mania, severe depression).

It is contraindicated for use in conjunction with certain medicinal products, in particular with:

  • CYP3A4 inhibitors (ketoconazole, itraconazole, ritonavir, etc.);
  • monoamine oxidase inhibitors;
  • thioridazine;
  • serotonin reuptake inhibitors, other drugs with serotonergic effect.

Taking this drug simultaneously with products containing ethanol (alcoholic, low-alcohol drinks) causes drowsiness, reduces activity, clouded consciousness, and increases the risk of side effects.

Do not use until the age of 18.

Application during pregnancy and lactation
This drug is not used in the therapy of females.

Method of administration and dosage
The drug is taken orally (swallowed whole with a full glass of 200 ml of water).
The time of admission does not depend on the meal.
The recommended starting dosage is 30 mg, which is taken 1-3 hours before intercourse.
Do not start treatment with a dosage of 60 mg. An increase in dosage is made only if there was no effect from taking the drug at a dose of 30 mg, and also if, after taking the minimum dosage, the patient did not observe moderate and severe adverse reactions, or symptoms that may indicate the possible development of loss of consciousness. If such symptoms are not observed, and the effect of taking the minimum dosage is insufficient, then the dosage can be increased to 60 mg per dose (per day).
It is also taken 1-3 hours before the expected time of intercourse.
It should be borne in mind that the frequency and severity of side effects when taking a dosage of 60 mg increases.
Do not exceed the maximum permissible dosage and frequency of taking Prilidji tablets – 1 time per day (24 hours).
If intercourse is not expected on this day, then the pill does not need to be taken.
The clinical need for continued therapy with this drug is assessed by the attending physician after the first four weeks of treatment, or at least after 6 (six) doses taken.
In the future, consultations should be carried out at least once every six months.
With mild severity of renal and hepatic insufficiency does not require adjustment.
The drug is not intended for elderly patients aged 65 years and older.

Dapoxetine overdose has not been reported at the moment.
In theory, exceeding the dosage can cause signs of poisoning – nausea, vomiting, tachycardia, tremors, agitation and fainting.
Gastric lavage, intake of enterosorbents, symptomatic treatment are recommended.
Dialysis, hemodialysis, forced diuresis, hemoperfusion, or blood transfusion are ineffective.
No known specific antidote has been identified to date.

Side effects
Adverse reactions have been observed with this drug:

  • depressive conditions, euphoria, mood swings, nervousness, anxiety, sleep disorders, bruxism, decreased sex drive, anorgasmia;
  • dizziness, headache, drowsiness, tremors, impaired taste, sedation, sudden drowsiness;
  • mydriasis, eye pain, visual disturbances;
  • vertigo, ringing in the ears;
  • hyperemia of the skin, hot flashes, hypotension, tachycardia, orthostatic hypertension, increased blood pressure;
  • nasal congestion, dry mouth, nausea, vomiting, diarrhea, constipation, dyspepsia, flatulence, urge to defecate;
  • skin rash, hyperhidrosis, itching, cold sweat;
  • erectile dysfunction, ejaculation disorders, paresthesia in the male genital areas;
  • allergy;
  • weakness, increased fatigue, fever, anxiety, drunkenness, withdrawal syndrome.

If you experience any unusual side effects as a result of taking this drug, you should consult your doctor about possible changes in the treatment regimen.

Storage conditions and periods
Prilidji is stored for up to 3 years. Does not require any special storage conditions.