Proctosedil M (framycetin sulfate) rectal capsules №20 vial


External and internal hemorrhoids; perianal eczema, proctitis.



Proctosedil M Composition
active ingredients: 1 capsule contains framycetin sulfate 5.00 mg hydrocortisone acetate 2.79 mg Esculoside 5.00 mg benzocaine 5.00 mg butamben 5.00 mg
excipients: lanolin, white soft paraffin, mineral oil, gelatin, glycerin, methylparaben (E 218), propyl parahydroxybenzoate (E 216), titanium dioxide (E 171), polyethylene glycol 6000, purified water.

Release form
Rectal capsules.

Pharmacological properties
Proctosedil M is a combined drug for the treatment of hemorrhoids and other diseases of the anorectal zone, the therapeutic effect of which is due to the pharmacological properties of the active substances that make up its composition. Hydrocortisone – GCS, has anti-inflammatory and anti-allergic effects, reduces serous discharge.
Framycetin is an antibiotic of the aminoglycoside group for topical use. Has a bactericidal effect against a number of gram-positive and gram-negative microorganisms, including S. aureus, S. faecalis, S. pneumonie, Proteus, Pseudomonas, E. coli, Klebsiella, Aerobacter and the like.
Esculoside reduces the increased fragility of capillaries.
Ethyl and butylaminobenzoate are local anesthetics. They relieve pain, itching and spasm of the anorectal sphincter.

Internal hemorrhoids perianal eczema proctitis; cracks in the anal area; postpartum hemorrhoids hemorrhoids in the pre- and postoperative period.

Hypersensitivity to drug components and other amide local anesthetics; tuberculous, viral, fungal infection or parasitic infections of the anorectal zone, neoplasms in the anus. The period of pregnancy and lactation, children under 3 years of age.

It is not used in pediatrics for children under 3 years of age.

Application during pregnancy or lactation
The use of the drug Proctosedil M during pregnancy and lactation is contraindicated.

Method of administration and dosage
In the acute period, rectal capsules should be used in the morning and in the evening, as well as after each act of defecation. After improvement of the condition, the drug should be used once a day. The rectal capsule should be inserted as deep as possible into the rectum. Proctosedil M should be used for a short time (no more than 7 days).
Do not swallow! After use, screw the cap tightly onto the capsule bottle.
Proctosedil M can be used alone or in combination with proctosedil ointment.

Long-term use in high doses enhances resorption and increases the risk of developing systemic effects of hydrocortisone.

Adverse reactions
Local reactions: rarely – burning, dryness of the rectal mucosa, secondary infection, delayed wound healing. Itching, pain, rash or discomfort in the anus, perianal dermatitis with or without skin atrophy may appear. Hypersensitivity reactions may occur, including cases of irritation, rash, dry skin, pustular acne.
Systemic side effects associated with hydrocortisone are possible if the drug is used for more than 7 days. With prolonged use in high doses, endocrine disorders are possible: crustal depression.
Methyl parahydroxybenzoate (E 218) and propyl parahydroxybenzoate (E 216) can cause allergic reactions (possibly delayed).

Shelf life
2 years.

Storage conditions
Store at a temperature not exceeding 25 ° C in a dry place out of the reach of children.