Prevention and treatment: ventricular arrhythmias; paroxysmal supraventricular tachyarrhythmias, including paroxysmal form of atrial flutter/fibrillation and paroxysmal circular tachycardia involving the AV node or additional pathways, if standard therapy is ineffective or contraindications for its implementation.
Composition and form of release
Propanorm is produced in tablets. The main component of the drug is propafenone hydrochloride.
Propanorm is intended for the prevention and treatment of paroxysmal, ventricular and supraventricular cardiac arrhythmias, such as atrial flutter, fibrillation, WPW syndrome, atrioventricular re-entry tachycardia. The drug can be used to prevent the onset of attacks of persistent monomorphic ventricular tachycardia.
Do not appoint for hypersensitivity to propafenone hydrochloride, poisoning with digoxin, severe forms of heart failure, cardiogenic shock, persistent hypotension, marked decrease in heart rate, bundle branch blockade, sinus node weakness, syndrome of “tachycardia, bradycardia” and infarction years old.
It is prescribed with extreme caution to patients who have chronic obstructive pulmonary disease, myasthenia gravis, heart failure, cardiomyopathy, arterial hypotension, the presence of a pacemaker, hepatic cholestasis, hepatic or renal failure and patients over 70 years of age.
Use during pregnancy and breastfeeding
Propanorm is not used in the treatment of pregnant women and is able to penetrate the breast milk, which makes it also impossible to take during the lactation stage.
Method of application and dosage
Propanorm is recommended to be consumed after a meal; the tablets are swallowed whole with a small amount of liquid. The dose of the drug is set by the doctor and can be adjusted during treatment. To eliminate attacks of paroxysmal atrial fibrillation, 600 mg of the drug is taken orally once.
Most often, the patient takes 450 mg per day, divided into 3 doses. If necessary, it is recommended to gradually increase the dose to 600 mg per day or 900 mg per day, divided into 3 doses.
Intoxication can develop with a single dose of the drug, twice the daily dose. With this, symptoms of intoxication appear an hour after taking the drug.
An overdose is characterized by the development in the patient of a decrease in blood pressure, drowsiness, vomiting, confusion, extrapyramidal disorders, ventricular tachycardia, seizures, pulmonary edema, delirium and intraventricular conduction.
To improve the patient’s condition, he undergoes gastric lavage, defibrillation, artificial ventilation of the lungs, the introduction of diazepam and dobutamine.
When taken, it is possible to develop bradycardia, ventricular tachycardia, angina pectoris, intraventricular conduction disturbances, orthostatic hypotension, taste changes, nausea, diarrhea, liver dysfunction, headaches, visual impairment, convulsions, decreased potency and the occurrence of various allergic reactions.
Storage conditions and periods
Propanorm is stored in a dry place out of the reach of children. The shelf life is 3 years.