Ramimed (ramipril) tablets 10 mg. №30

$26.00

Ramimed tablets are prescribed for the treatment of arterial hypertension, congestive heart failure, diabetic and nondiabetic nephropathy, postinfarction myocardial dysfunction and for the prevention of cardiovascular diseases.

Category: Manufacturer: Cyprus/Malta

Description

Composition and form of release
Ramimed is produced in the form of capsule-like, flat tablets, without a shell, with a notch on one side and on the sides. Tablets 5 mg light pink with the marking “R 3”. Tablets 10 mg white or almost white, marked “R 4”. The main element in one tablet is ramipril 10 mg. As additional substances: lactose monohydrate, corn starch, sodium bicarbonate, sodium stearyl fumarate, sodium croscarmellose, dyes. 30 tablets in a blister pack, 3 blisters of 10 tablets in one carton pack.

Pharmacological properties
Ramimed tablets are a cardiovascular drug that has an antihypertensive effect, helps to lower blood pressure and dilate blood vessels.

Indications for use
Ramimed tablets are prescribed for the treatment of arterial hypertension, congestive heart failure, diabetic and nondiabetic nephropathy, postinfarction myocardial dysfunction and for the prevention of cardiovascular diseases.

Contraindications
The drug has contraindications for: renal stenosis, arterial hypotension, renal failure, angioedema, primary hyperaldosteronism, instability of hemodynamic parameters, simultaneous treatment with drugs that contain aliskiren and use with extracorporeal treatment methods, including dialysis or hemofiltration. Personal intolerance to the constituent components and childhood are also a contraindication.

Application during pregnancy and lactation
The tool should not be used by pregnant women and nursing mothers, as well as women planning pregnancy.

Method of administration and dosage
The drug Ramimed with arterial hypertension is prescribed at 2.5 mg of ramipril per day, if necessary, then within 15-30 days the dose is increased until the maximum permissible dose of 10 mg per day is reached. If after taking the pills there is a significant decrease in blood pressure, then it is worth starting therapy with 1.25 mg.

  • Patients suffering from heart failure begin treatment with 1.25 mg per day, every 1-2 weeks the dose can be doubled to the maximum daily dose of 10 mg.
  • Patients who need to take pills to prevent cardiovascular diseases begin treatment with 2.5 mg per day, the dose can be increased within 1-2 weeks, and then after 2-3 weeks it can be increased to the maximum daily dose of 10 mg.
  • For patients who have suffered myocardial infarction, the initial dose is 2.5 mg in the morning and in the evening (twice a day). If you need therapy, you can start with 1.25 mg twice a day for 2 days after a heart attack. And only after that, the dose can be increased every 1-3 days, doubling it to a maximum daily dose of 10 mg.
  • Patients who have kidney disease, provided that creatinine clearance is from 10 to 30 ml / min, take 1.25 mg per day, if creatinine clearance is from 30 to 60 ml / min, take 2.5 mg per day. The maximum permissible daily dose for such patients is 5 mg. In the case when creatinine clearance is from <60 ml / min, take 2.5 mg per day. The maximum permissible daily dose for such patients is 10 mg.
  • For patients in old age, the minimum initial dose is 1.25 mg; in the future, dose titration should be carried out more gradually.
  • Patients with diabetic and non-diabetic nephropathy should begin therapy with 1.25 mg ramipril per day in the morning. Then the dose can be increased every 2 weeks up to a maximum daily dose of 5 mg.
  • For patients with impaired liver function, the maximum daily dose is 2.5 mg, treatment should be carried out under the strict supervision of a physician.
  • In cases where the patient takes diuretics, it is necessary to stop taking diuretics or reduce the dose before starting treatment. The doctor selects and changes the dose for each patient individually. If diuretics are needed, then treatment begins with a dose of 1.25 mg, while monitoring kidney function and blood potassium levels. The dose adjustment depends on the blood pressure level.
  • Patients with diabetes and with at least one cardiovascular risk factor begin treatment with 2.5 mg per day, the dose can be increased within 1-2 weeks, and then after 2-3 weeks it can be increased to the maximum daily dose of 10 mg.

The drug is taken orally without chewing, drinking plenty of water, Ramimed can be used before and after meals, as well as during meals.

Overdose
In case of an overdose, there may be: bradycardia, arterial hypotension, electrolyte imbalance, shock and renal failure. In case of drug intoxication, the patient needs to do a gastric lavage, take sodium sulfate and adsorbents to cleanse the body, take measures to restore stable hemodynamics. The patient’s condition must be monitored and supportive and symptomatic therapy carried out.

Side effects
When taken, side reactions may occur: vomiting, angina pectoris, heart failure, diarrhea, chest pain, vertigo, hemolytic anemia, nausea, pancytopenia, myelodepression, thrombocytopenia, agranulocytosis, eosinophilia, vasculitis. Also hematological disorders, cough, syncope, autoimmune diseases, upper respiratory tract infections. Dizziness, asthenia, headache, impaired renal function, oliguria, proteinuria, erythema multiforme, edema, urticaria, photosensitivity are common.
In rare cases, arrhythmias, dry mouth, increased salivation, anorexia, dyspepsia, constipation, dysphagia, abdominal pain, pancreatitis, hepatitis, gastroenteritis, cholestatic jaundice, pharyngitis, dyspnoea, laryngitis, sinusitis, tracheobronchitis, bronchitis, bronchitis are possible. Sometimes amnesia, drowsiness, depression, neuralgia, sleep disorders, tremors, hearing loss, paresthesia, visual impairment, neuropathy, anaphylactoid reactions, weight loss, seizures, increased levels of urea nitrogen and creatinine, arthralgia, angioedema, myalgia, changes in saturation may occur bilirubin, uric acid, glucose, hyperkalemia.

Storage conditions and periods
The drug should be stored at temperatures up to + 25 ° C, in its original packaging, out of sight of children. After 2 years from the date of manufacture, the drug cannot be used.