Ranexa 1000 (ranolazine) tablets with prolonged release 1000 mg. №60

$272.00

The drug Ranexa 1000 is a cardiac drug, the action of which is due to the suppression of the late flow of sodium ions into myocardial cells, a decrease in intracellular sodium accumulation and a decrease in the excess of intracellular calcium ions, which helps to relax the myocardium and reduce gastro-diastolic tension.

Category: Manufacturer: Germany

Description

Release form, composition
The Ranexa 1000 preparation is produced in the form of pale yellow biconvex oval-shaped tablets, which are coated, with the inscription “1000” on one side.
This drug contains the main component: ranolazine (1000 mg), as well as additional substances: microcrystalline cellulose, hypromellose, copolymer of ethyl acrylate and methacrylic acid (1: 1), magnesium stearate, glycerol triacetate, sodium hydroxide, lactose, titanium dioxide, polyethylene glycol 3350 , iron oxide yellow and carnauba wax.

Pharmacological properties
The drug Ranexa 1000 is a cardiac drug, the action of which is due to the suppression of the late flow of sodium ions into myocardial cells, a decrease in intracellular sodium accumulation and a decrease in the excess of intracellular calcium ions, which helps to relax the myocardium and reduce gastro-diastolic tension.

Indications for use
The drug is used and prescribed for stable angina pectoris.

Contraindications
Ranexa 1000 is usually very well tolerated, but still there are contraindications to the use of the drug, such as: renal and hepatic failure, individual intolerance to the constituent substances, children under 18 years of age. Concomitant use with potent CYP3A4 inhibitors (itraconazole, voriconazole, ketoconazole, posaconazole, telithromycin, clarithromycin, HIV protease inhibitors, nefazodone, etc.), as well as in combination with antiarrhythmic drugs of class Ia (quinialidine) or class III ( dofetilide and others), except for amiodar.

Pregnancy and breastfeeding period
The use of Ranexa 1000 is contraindicated during pregnancy and lactation.

Mode of application
Ranexa 1000 is taken regardless of food, without chewing, without breaking.
The recommended dose is 500 mg 2 times a day. After 2-4 weeks of use, if necessary, the dose can be increased to 1000 mg 2 times a day. The maximum dose per day should not exceed 2000 mg.
If taking the pills caused side effects, for example, nausea, dizziness, vomiting, the dose is reduced by 500 mg, but if the reaction to the drug persists, it is necessary to stop treatment.

Overdose
An overdose of Ranex 1000 often leads to dizziness, vomiting and nausea.
In case of poisoning with pills, symptomatic treatment should be applied.

Adverse reactions
Side effects when using Ranexa 1000 are manifested in the form of: anorexia, dehydration, decreased appetite, anxiety, confusion, insomnia, dizziness, lethargy, headache, hypesthesia, loss of consciousness, drowsiness and tremor.
Also possible: blurred vision, hallucinations, visual disturbances, diplopia hypotension, hot flashes, cold extremities, cough, shortness of breath, nosebleeds, tinnitus, a feeling of a lump in the throat, nausea, constipation, abdominal pain, vomiting, dry mouth.
Taking pills can cause: dyspepsia, stomach discomfort, flatulence, pancreatitis, oral hypesthesia, erosive duodenitis, pruritus, angioedema, hyperhidrosis, allergic dermatitis, cold sweat, urticaria, rash, muscle cramps, pain in the extremities, edema , dysuria, chromaturia, acute renal, urinary retention, failure, erectile dysfunction, asthenia, fatigue and peripheral edema.

Storage conditions
Storage of the drug does not require special conditions: the temperature is no more than +25 ° C and a place that children do not have access to.
The shelf life of the tablets is 5 years.