Symptomatic treatment of osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.
Active ingredient: celecoxib.
Ranselex is produced in the form of 200 mg capsules.
It is a non-steroidal anti-inflammatory (NSAID), antirheumatic drug. Acts by a specific inhibitory effect on cyclooxygenase-2 (COX-2). This blocks the formation of prostaglandins. Slightly affects the activity of COX-1. The drug has anti-inflammatory, antipyretic and analgesic (pain relieving) effects.
Ranselex is indicated for degenerative and inflammatory diseases of the musculoskeletal system (rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, psoriatic arthritis, etc.).
It is forbidden to use Ranselex:
- with hypersensitivity to the components of this medication;
- with hyperergic reactions in the past associated with the treatment of NSAIDs;
- with bronchial asthma;
- with exacerbation of duodenal / gastric ulcer;
- with severe blood clotting disorders;
- with bleeding from the digestive tract;
- with severe heart failure;
- with gastrointestinal bleeding in the past;
- with severe renal / hepatic impairment;
- after coronary artery bypass grafting;
- with severe violations of the heart (heart failure);
Application during pregnancy and lactation
Method of administration and dosage
Ranselex is used internally (regardless of food), drink plenty of fluids. The standard dosage is 200 mg once or twice a day.
In rheumatoid arthritis, 200-400 mg / day is indicated, divided into 2 doses.
In case of an overdose, symptoms such as drowsiness, nausea, and abdominal pain occur. Gastrointestinal bleeding may occur. There is no specific antidote. In case of an overdose in the first four hours, gastric lavage and the use of enterosorbents are indicated. The following shows the maintenance and symptomatic therapy.
Side effects that may occur during use include abdominal pain, dizziness, nervousness, blurred vision, shortness of breath, asthma attacks, anemia, various hypersensitivity reactions, arterial hypertension, nausea, tachycardia, malaise, headaches, vomiting, asthenia, hyperkalemia , drowsiness, nightmares, diarrhea, thrombocytopenia (decrease in the number of platelets), constipation, pancytopenia (decrease in the number of all blood cells), fear, purpura, kidney failure, flatulence (bloating), itching, swelling, hypothermia (decrease in temperature), hyperhidrosis (excessive sweating), skin rashes, hot flashes, bronchospasm, jaundice, dyspepsia, erythema, interstitial nephritis, gastritis, dermatitis, stomatitis, angioedema, bleeding from the digestive tract, urticaria, oliguria, ulcer / perforation of the intestine / duodenum / duodenum the appearance of blood in the urine), erythema polyform, facial edema, hepatitis, dysuria, cholestasis, urinary retention (delay urination), Stevens-Johnson syndrome.
If any undesirable reactions occur, the patient should stop taking this medication and contact his doctor.
Storage conditions and periods
Store Ranselex is required in places protected from light. Temperature range: up to + 25 ° С.
The shelf life of the tablets is two years.