External and internal hemorrhoids, cracks in the anus, erosion and microtrauma of the anus, anal itching.
Composition Relief Ultra
Main active ingredients: zinc sulfate, hydrocortisone.
Auxiliary components: methyl parahydroxybenzoate, propyl parahydroxybenzoate, anhydrous calcium hydrogen phosphate, cocoa butter, magnesium stearate.
It is produced in the form of rectal suppositories. 1 suppository contains 10 mg of hydrocortisone acetate and 11 mg of zinc sulfate monohydrate.
This drug Relief Ultra belongs to the group of corticosteroid and antimicrobial drugs, as well as their combinations, intended for the treatment of certain diseases in proctology.
The effect of the drug is explained by the characteristics of its main active ingredients. The main active ingredients are zinc sulfate in the form of monohydrate and hydrocortisone in the form of acetate.
Hydrocortisone is a glucocorticosteroid drug that produces mild anti-inflammatory, as well as antiallergic and decongestant (antiexudative) effects.
Zinc sulfate (in sulfate form) has the property of healing wounds and erosion both on the skin and on the mucous membrane.
It has antiparasitic and highly effective bactericidal and antimicrobial effects.
Promotes the normalization of the epithelium in terms of hydration.
This drug Relief Ultra is used to treat diseases in proctology, in particular:
- external and internal hemorrhoids;
- cracks, fistulas;
- ulcers, erosions of the perianal region and rectum, which are accompanied by severe inflammatory manifestations;
- proctitis, anal itching;
- eczema, dermatitis of the perianal region.
The drug in question is contraindicated for use in cases where the patient has severe hypersensitivity (allergy) to the main or one of the auxiliary components.
Also contraindicated for:
- specific (bacterial, fungal, viral, tuberculous) lesions of the anorectal region;
- neoplasms in the anus;
- thromboembolic disease;
- intestinal obstruction;
- abscesses, risk of perforation;
- fistulas, fresh intestinal anastomoses or fistulous passages.
Use with caution while treating with anticoagulants, hypoglycemic agents, barbiturates, diuretics, cardiac glycosides.
When used simultaneously with other GCS (both topical and oral), the likelihood of systemic effects may increase.
Application during pregnancy and lactation
The use of strong / very strong GCS topically during pregnancy may be associated with placental insufficiency and low birth weight. Therefore, this drug is contraindicated in the treatment of pregnant women.
If it is necessary to use the drug, if a woman is lactating, then breastfeeding should be suspended for the duration of treatment.
Method of administration and dosage
Designed for use in proctology.
Pre-wash the skin around the anus with cool water, clean the affected area with a moistened soft cloth, dry it carefully with toilet paper or a soft cloth. Before the introduction of the suppository, it is necessary to remove the protective plastic sheath from it.
Insert the suppository into the anus as deeply as possible. Inject one suppository 2 to 4 times a day (at night, in the morning and after each bowel movement). The duration of the course of treatment should not exceed 7 days.
The correction of the duration of treatment, dosages and treatment regimens is determined by the attending physician individually, depending on the individual indicators of the course of the disease.
Overdose for a long period can cause hypercortisolism.
Long-term use in large doses enhances resorption and increases the risk of developing systemic effects of hydrocortisone, such as menstrual irregularities, increased blood pressure, delayed wound healing, muscle weakness, insomnia, increased blood sugar, hirsutism, glaucoma, etc.
If accidentally swallowed, gastrointestinal disorders (nausea, stomach pain) may occur.
The drug is usually well tolerated. In cases of hypersensitivity, reactions such as:
- nausea, vomiting, diarrhea;
- rash, dermatitis, allergic urticaria;
- hyperemia, swelling, itching, atrophic skin changes, hypertrichosis;
- Cushing’s syndrome, hyperglycemia, glucosuria, growth retardation, intracranial hypertension;
- rosace-like and perioral dermatitis, with or without skin atrophy;
- the “rebound” effect, which can cause steroid dependence;
- delayed wound healing;
- depigmentation, hypertrichosis.
Storage conditions and periods Relief Ultra
Expiration date – 2 years from the production date indicated on the package.
The storage temperature should not exceed 25 ° C.