Liver function disorders due to acute or chronic liver damage (toxic, alcoholic, drug-induced hepatitis); complex treatment of viral hepatitis (in addition to etiotropic therapy).
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active substances: 1 liter of solution contains succinic acid – 5,280 g; meglumine – 8.725 g; inosine – 2,000 g; methionine – 0.750 g; nicotinamide – 0.250 g;
Excipients: sodium chloride, sodium hydroxide, potassium chloride, magnesium chloride hexahydrate, water for injections.
Solution for infusion.
Remaxol is a balanced infusion solution that has a hepatoprotective effect. Under the action of the drug accelerates the transition from anaerobic to aerobic processes, improves the energy supply of hepatocytes, increases the synthesis of macroergs, increases the resistance of hepatocyte membranes to lipid peroxidation, restores the activity of antioxidant enzymes.
The effect of the drug Remaxol:
- reduces cytolysis, which is manifested in the reduction of indicator enzymes: aspartate aminotransferases, alanine aminotransferases;
- helps reduce bilirubin and its fractions, improves the excretion of direct bilirubin in bile. Reduces the activity of excretory enzymes of hepatocytes – alkaline phosphatase and gamma-glutamyltranspeptidase, promotes the oxidation of cholesterol to bile acids;
- does not inhibit cytochromes responsible for drug metabolism (CYP 1A2, CYP 3A4, CYP 2C9, CYP 2C19, CYP 2D6);
- does not cancel the antitumor effect of cytostatics (platinum drugs, antimetabolites, alkaloids), does not increase their toxic effect on the body, does not stimulate tumor growth.
Liver dysfunction due to acute or chronic damage (toxic, alcoholic, drug-induced hepatitis);
comprehensive treatment of viral hepatitis (in addition to etiotropic therapy).
Individual sensitivity to the components of the drug.
Method of application and dosage
Remaxol is administered only intravenously in a daily dose of 400 ml to 800 ml for 3-12 days, depending on the severity of the disease. The rate of injection is 40-60 drops (2-3 ml) per minute.
There is no information about drug overdose.
With rapid administration of the solution may cause adverse reactions (redness of the skin of varying degrees, a feeling of heat, irritation in the throat, dry mouth), it does not require discontinuation of the drug.
Allergic reactions in the form of a rash and an itch which are eliminated by use of antihistamines are possible.
Rare side effects include nausea, headache and dizziness.
Due to the activation of aerobic processes in the body, it is possible to reduce the concentration of glucose and increase the level of uric acid in the blood.
3 years. Do not use after the expiry date stated on the package.
In a place protected from light at a temperature not exceeding 25 ºC.
Keep out of reach of children.