Respix (ambroxol hydrochloride) spray oral solution 10 mg/0.2 ml. 13 ml. vial


Treatment of acute and chronic respiratory diseases accompanied by violation of bronchial secretion and evacuation of secretions ( including acute and chronic bronchitis, chronic obstructive pulmonary diseases, pneumonia, bronchiectatic disease, bronchial asthma, cystic fibrosis, laryngitis, tracheitis). Use in preparation for bronchoscopy and after the study.



Composition and form of release Respix 
Main active ingredient: ambroxol hydrochloride.
Excipients: trometamol, macrogol hydroxystearate, glycerin, potassium acesulfame, xylitol, sodium benzoate, levomenthol, ammonium glycyrizate, ethanol 96%, sodium hydroxide, purified water.
It is produced in the form of a spray, in 13 ml vials equipped with a dispenser, 50 mg of ambroxol in 1 ml of the drug (1 dose contains 0.2 ml of the drug or 10 mg of ambroxol hydrochloride.

Pharmacological properties Respix 
This drug belongs to the group of a set of drugs used in the treatment of diseases of the lower respiratory system, which are accompanied by a dry cough with poor sputum separation.

The main active ingredient is ambroxol. It is produced from the plant Adhotoda vazika as one of the forms of bromhexine, being its active metabolite.
Unlike bromhexine, it does not have a methyl group, as well as an additional hydroxyl group. There is no information about the exact mechanism of its action, but it is known that ambroxol produces an active secretolytic, expectorant and secretomotor effect.
Shows activity after half an hour after ingestion, exerting its effect for 6 to 12 hours in a row. The drug activates bronchial secretion, while at the same time improving the process of removing the drug from the respiratory tract.
Promotes a decrease in the viscosity of secreted secretions in patients, regardless of the patient’s age.

Indications Respix 
This drug can be used in the complex treatment of acute and chronic bronchopulmonary diseases, which are accompanied by dry cough, impaired mucus formation and excretion.
Before starting treatment, you should consult your doctor.

The drug in question is contraindicated for use in cases where the patient has severe hypersensitivity (allergy) to the main or one of the auxiliary components.
Should not be used concomitantly with drugs that block the cough reflex due to the likelihood of excessive accumulation of bronchial secretions in the lungs.
It is not used in pediatrics until the age of 12.

Application during pregnancy and lactation
This drug is contraindicated for pregnant women and women during lactation.

Method of administration and dosage
The drug is administered orally, in the form of injections into the oral cavity 3 times a day, that is, 30 mg 3 times a day.
After the drug enters the oral cavity, it must be swallowed. Preferably taken with or immediately after meals.
High secretion of liquid mucus requires a large amount of fluid consumed.
The duration of the course of treatment is no more than 5 days.
The patient should consult a doctor if the symptoms of the disease did not disappear during the use of the drug or if adverse reactions are observed that are not indicated in the instructions for medical use of the drug.

Overdose in significant doses has not been observed to date.
In rare cases, nausea and diarrhea, dyspeptic symptoms, disorders of the gastrointestinal tract were noted.
In case of overdose, you should rinse the stomach, take sorbents.

Side effects
Usually, this drug is well tolerated without causing complications.
In theory, the use of this drug can occasionally cause allergic side reactions, in particular, such as:

  • allergic urticaria, itching, rash, hyperemia;
  • nausea, vomiting, abdominal pain, heartburn;
  • upset gastrointestinal tract;
  • dysgeusia, dry mouth, throat.

If side effects occur, the drug should be discontinued, symptomatic therapy should be undertaken, consult a doctor and the treatment regimen should be adjusted.

Storage conditions and periods
Expiration date – 3 years from the date of manufacture indicated on the package. After the first use, the shelf life is reduced to 1 month.

The storage temperature should not exceed 25 ° C.