Depression. Treatment of any type of depression, including reactive and severe depression, as well as depression accompanied by anxiety. If there is a satisfactory response to treatment, continued therapy is effective for preventing relapses of depression. Obsessive-compulsive disorder. Treatment of symptoms and prevention of relapses of obsessive-compulsive disorder. Panic disorder. Treatment of symptoms and prevention of relapses of panic disorder with or without concomitant agoraphobia. Social phobias/social anxiety disorders. Treatment of social phobias/social anxiety States. Generalized anxiety disorder. Treatment of symptoms and prevention of relapses of generalized anxiety disorder. Posttraumatic stress disorder. Treatment of post-traumatic stress disorder.
Composition and form of release Rexetin
Active ingredient: paroxetine.
Release in tablet form (30 mg).
Rexetin is an antidepressant. Inhibits the reverse neuronal uptake of serotonin in the brain. Little effect on the seizure of norepinephrine, dopamine. It also has anxiolytic (anti-anxiety), psychostimulating properties.
- with obsessive-compulsive disorder (OKP);
- with generalized anxiety disorder;
- with depression of various causes, incl. states accompanied by anxiety;
- with panic disorder, incl. with agoraphobia (fear of being in a crowd);
- with social phobia;
- with post-traumatic stress disorder.
You can not appoint Rexetin :
- with allergies to the components of the drug;
- during treatment with monoamine oxidase inhibitors and within two weeks after;
- during pregnancy / lactation.
- under the age of 18.
Application during pregnancy and lactation
Method of administration and dosage
Rexetin should be taken once a day, without chewing, preferably in the morning with meals.
Depending on the clinical condition of the patient, the dosage of the drug can be changed after 2-3 weeks.
The recommended daily dose for depression is 20 mg. The healing effect usually develops gradually. The daily dose can be increased by 10 mg at intervals of one week, until a therapeutic effect is achieved. The maximum dose that can be taken per day is 50 mg.
Signs of an overdose: tremor, nausea, vomiting, dilated pupils, general agitation, dry mouth, increased sweating, dizziness, drowsiness, redness of the facial skin.
When overdosing, it is necessary to ensure airway patency, oxygenation, gastric lavage, prescribe enterosorbents. Continuous monitoring of cardiac and other vital functions is recommended.
- Digestive disorders: decreased appetite, nausea, constipation / diarrhea, increased liver function tests, severe liver dysfunction.
- Neurological disorders: drowsiness, tremors, weakness, fatigue, paresthesia, irritability, insomnia, headache, dizziness, extrapyramidal disorders, somnambulism, epileptiform seizures, orofacial dystonia, increased intracranial pressure.
- Vegetative disorders: increased sweating, dry mouth.
- Perceptual disorders: visual impairment, mydriasis, an attack of acute glaucoma.
- Cardiovascular disorders: tachycardia, ECG changes, instability of blood pressure, fainting.
- Urinary and sexual disorders: violation of ejaculation, difficulty urinating, changes in libido.
- Dermatological reactions: redness of the skin, edema of the face and extremities, subcutaneous hemorrhages, anaphylactic reactions (bronchospasm, hives, angioedema), pruritus.
- Electrolyte imbalance: hyponatremia, edema, impaired consciousness, epileptiform symptoms.
- Others: myopathies, myalgia, hyperglycemia, hyperprolactinemia, fever, galactorrhea, hypoglycemia, development of a flu-like state, thrombocytopenia, increase / decrease in body weight, bleeding.
- Abrupt withdrawal of the drug can cause sensory disturbances, dizziness, fear, agitation, sleep disturbances, tremors, increased sweating, confusion, nausea, therefore, the termination of therapy should be done gradually (dose reduction every second day).
Storage conditions and periods
At 15-30 ° C. The shelf life is 4 years.