Treatment of infections caused by microorganisms sensitive to spiramycin: Confirmed tonsilopharyngitis caused by beta-hemolytic group a streptococci (as an alternative to treatment with beta-lactam antibiotics, especially if they can not be used). Acute sinusitis (taking into account the microbiological characteristics of the infection, the use of macrolides is indicated when treatment with beta-lactam antibiotics is not possible). Superinfection in acute bronchitis. Exacerbation of chronic bronchitis. Non-hospital pneumonia in patients who do not have risk factors, severe clinical symptoms, or clinical factors indicating the pneumococcal etiology of the disease. In case of suspected atypical pneumonia, the use of macrolides is advisable regardless of the severity of the disease and anamnesis. Skin infection with benign course: impetigo, impetiginized, ecthyma, infectious dermo-hypodermic (especially face), erythrasma. Infection of the oral cavity. Non-gonococcal genital infections. Chemoprophylaxis of relapses of acute rheumatic fever in patients who are allergic to beta-lactam antibiotics. Toxoplasmosis in pregnant women. Prevention of meningococcal meningitis in individuals who are contraindicated to use rifampicin: for the purpose of eradication of a micro-organism (Neisseria meningitidis) in the nasopharynx. spiramycin is indicated as a preventative treatment: for patients after treatment and before returning to public life; for patients who have had contact with a person with sputum discharge during the 10 days preceding his/her hospitalization. Spiramycin is not intended for the treatment of meningococcal meningitis. Official recommendations regarding the proper use of antibacterial agents should be followed.
Rovamicin Composition and form of release
The main active ingredient is spiramycin, additional components. Available in tablets at a dosage of 3 million IU.
It is a macrolide antibiotic with a bacteriostatic effect. Prescribed for the treatment of infections and inflammatory processes of the upper and lower respiratory tract, which are caused by bacteria sensitive to it (streptococci, meningococci, meningococci, leptospira, campylobacter, Staphylococcus aureus, ureaplasma), as well as moderately sensitive to spiramycin bacterium bacteria.
It should be noted that Pseudomonas bacteria, enterobacteria, and methicillin-resistant staphylococci are insensitive to it. It is active against pneumonia caused by atypical microorganisms.
It is used to treat diseases of the skin (erysipelas, abscesses, phlegmon), venereal diseases (chlamydia, toxoplasmosis, syphilis, gonorrhea), as well as diseases caused by non-gonococcal infections, and which the genitourinary system is susceptible to.
It is forbidden for use in case of an allergic reaction of the body to one of the components of the drug. Also not applicable if the patient suffers from severe liver disease.
Rovamicin is not combined, that is, it is not used concomitantly with drugs that cause flutter or fibrillation of the myocardial ventricles, including some antiarrhythmic drugs. Also incompatible with neuroleptics, nondihydropyridine calcium channel blockers, beta-adrenergic blockers, erythromycin, sultopride, cisapride, vincamine, clondine.
Application during pregnancy and lactation
It has no contraindications when administered to pregnant women or nursing mothers.
Method of administration and dosage
Due to the high efficiency of the drug, it does not require long-term use. Usually, a 5-day intake is sufficient to combat fairly severe infections. In particular, when using the tablet form, a maximum of 3 million IU is prescribed from two to three times a day, while the daily dose does not exceed 9 million IU. If it is necessary to use this drug in order to prevent meningitis infection, it is enough to take 3 million twice a day, also for five days.
Overdose usually causes dyspeptic disorders, with infusion, complications of the cardiovascular system are possible, in particular, the Q – T interval may be lengthened. Treatment of symptoms is recommended.
Pain in the epigastrium, reactions from the gastrointestinal tract in the form of nausea, vomiting, sometimes an allergic reaction. Pseudomembranous colitis, phlebitis, hemolytic anemia may develop, and the level of transaminases may increase.
Storage conditions and periods Rovamicin
The shelf life of the tablets are 3 years (at temperatures up to 25 ° C).