Rozamet (metronidazole) cream 1% 25 g.


Local treatment of inflammatory papules and pustules in rosacea and vulgar acne, rosacea-like steroid dermatitis.

Category: Manufacturer: Croatia


Composition and form of release
Active substance: metronidazole (10 mg / g).
Rozamet is produced in the form of a cream for external use.

Rozamet Pharmacological properties
It is an antimicrobial agent used in dermatology. The effectiveness is ensured by the presence of metronidazole in this drug, which is 5-nitroimidazole. The mechanism of its action is due to the ability to interact with deoxyribonucleic acid (DNA) of cells of microorganisms. In this case, the production of nucleic acids is inhibited and bacteria die. Active against protozoa: Entamoeba histolytica, Trichomonas vaginalis, Giardia lamblia, as well as facultative anaerobes Bacteroides spp. (Bacteroides ovatus, Bacteroides fragilis, Bacteroides distasonis, Bacteroides thetaiotaomіcron, Bacteroides vulgaris), Prevotella spp. (Prevotella buccae, Prevotella bivia, Prevotella disiens), Fusobacterium spp., Veіllonella spp., Some facultative obligate (Clostrіdium spp.), Facultative (Eubacterіum spp., Peptococcus spp., Peptostrobate. Gardnerella vaginalis. Aerobes are insensitive to metronidazole, but in the presence of mixed flora (anaerobes + aerobes), it acts synergistically with antibiotics.

Rozamet is prescribed for the local treatment of rosacea, rosacea-like steroid dermatitis, acne vulgaris, skin infections, bedsores, burns, eczema, seborrheic eczema, oily seborrhea, seborrheic dermatitis, trophic ulcers (with varicose veins, diabetes mellitus), wounds that slowly heal, hemorrhoids, cracks in the anus, balanoposthitis, vulvovaginitis.

Rozamet cannot be prescribed:

  • if you are allergic to metronidazole, nitroimidazole derivatives;
  • with intolerance to auxiliary components;
  • during pregnancy;
  • during lactation;
  • children under 18.

It is used with caution in blood diseases, leukopenia, in diseases of the central nervous system (for example, epilepsy), in liver failure.

Application during pregnancy and lactation
This medication is contraindicated during pregnancy.
The active ingredient is able to penetrate into breast milk, therefore, breastfeeding during the treatment period should be canceled. You can resume feeding no earlier than 48 hours after the end of the use of this medication.

Method of administration and dosage
Rozamet is used for external use only.

The cream is applied to cleansed skin in a thin layer and rub in lightly 1-2 times / day.
The duration of treatment depends on the indications.

Overdose symptoms with Rosamet: leukopenia, vomiting, abdominal pain, neuropathy, diarrhea, impaired coordination, paresthesia, metallic taste in the mouth, dizziness, convulsions.
Treatment: discontinuation, maintenance therapy.

Side effects:

  • Digestive upsets: dry mouth, nausea, change in taste, metallic taste, abdominal cramping, loss of appetite, constipation or diarrhea.
  • Local reactions: irritation, pain, itching, burning.
  • Neurological disorders: headache, dizziness.
  • Hematopoiesis changes: leukopenia, leukocytosis.
  • Allergic reactions: itching of the skin, urticaria, rash.

There may be a reddish-brown staining of urine.

Storage conditions and periods
At 15-25 ° С no more than 2 years.