Salofalk (mesalazine) granules 1.5 g. №35


Treatment of exacerbations and prevention of recurrences of ulcerative colitis limited to the rectum.

Category: Manufacturer: Germany


Salofalk Composition and form of release
Salofalk is produced in various forms for taking the drug – in tablets, granules, rectal suppositories, suspensions for rectal administration.
Granules – 1500 mg each.
The active active ingredient is mesalazine (5-aminosalicylic acid), which has antioxidant, anti-inflammatory, antimicrobial properties that act directly in the intestines.

Pharmacological properties
It belongs to the category of agents acting on the foci of inflammation. Shows itself as an antioxidant.
Available in various application forms.
The drug begins to act from an hour and a half after administration or administration (depending on the form of application).
The forms of oral administration of the medication are protected by the membrane from the destructive effect, and therefore they fall as intended in the place of action – the small and large intestines.
Salofalk is not affected by factors such as pH, other medications and food intake.
The withdrawal of the drug is carried out by the kidneys.

Treatment and prevention of gastrointestinal diseases:

  • Crohn’s disease (chronic inflammatory disease with nodules)
  • ulcerative colitis (chronic inflammatory disease of the colon mucosa).

Do not use the drug in children under 2 years of age.
Allergic reactions and high sensitivity to the active substance of the drug or auxiliary components, compounds from the salicylate group.
Salofalk is unacceptable to use in the presence of severe functional disorders of the liver and kidneys, peptic ulcer of the stomach and / or duodenum.
Patients who suffer from hemorrhagic diathesis and diseases of the blood and circulatory system should also refrain from taking the drug.

Application during pregnancy and lactation
If you follow strict indications and under the supervision of a doctor, the drug can be used up to 12 weeks of pregnancy.
It is forbidden to take Salofalk one month before the expected birth, provided that the disease does not require constant intake of the drug.
Information about taking the drug during breastfeeding is not enough, therefore it is recommended to refrain from treatment with Salofalk while breastfeeding.
If you are planning a pregnancy, you should stop taking the medication or keep the dose to a minimum.

Method of administration and dosage
First of all, the dosage and duration of treatment depends on the form of release of Salofalk, the course of the disease, its severity and localization.
The average recommended dose for mild to moderate Crohn’s disease and ulcerative colitis is 500 mg three times a day. In case of complications, the dose is increased by three to four times.
The average duration of the drug is 2 to 3 months.
Salofalk in the form of granules is also taken three times a day. The granules are swallowed without chewing with plenty of water.
Not prescribed for children under 6 years of age. From this age, granules are prescribed for three times a day at the rate of 30-50 mg per kilogram of weight. For prophylactic purposes, the dose is reduced by half.
Children weighing more than 40 kg can use the “adult” dose.

Usually, there is no overdose at a controlled dose. Overdose symptoms appear the same as the side effects.

Side effects
Salofalk is well tolerated, but sometimes (extremely rarely) patients notice pain in the joints and muscles.
Individual reactions of some people can manifest themselves in the form of allergic reactions: urticaria, spasms in the bronchi, itching, myo- and pericarditis, and fever.
In some cases, problems arise with the circulatory system, the organs of the digestive tract – abdominal pain, nausea, vomiting, inflammation in the pancreas, hepatitis and others.
Dizziness and headaches are extremely rare.
Mesalazine and drugs similar in structure to it can cause systemic lupus erythematosus syndrome.

Storage conditions and periods
All dosage forms of Salofalk are stored for no more than 3 years, with the exception of the suspension – it is stored for no more than 2 years.
Store in a dark and dry place, away from children, at a temperature not exceeding 25 C.