As a prophylactic: for newborns to prevent purulent and inflammatory skin diseases and for surgical patients to prevent wound infection. As a treatment: for infectious and inflammatory diseases of the skin and mucous membranes of bacterial and fungal etiology, including Candida albicans; in dentistry-for periodontitis, aphthous stomatitis, ulcerative – necrotic gingivostomatitis and other lesions of the oral mucosa; in otolaryngology-for angina, diseases of the middle ear and external auditory passage; in surgery – for infected burns, long – term non – healing wounds and ulcers; in gynecology-for endocervicitis, colpitis, vaginitis, cervical erosion; in dermatology – with pyoderma, superficial blastomycosis, dermatomycosis.
active substance: sanguiritrin;
1 ml of solution contains 2 mg of sanguiritrin;
excipients: ethanol 96%, purified water.
Solution for external use.
Sanguiritrin is obtained from the grass Macleaya cordata (Willd.) R.Br. and Macleaya microcarpa (Maxim.) Fedde family of poppies (Papaveraceae). Sanguiritrin is a mixture of bisulfates of two similar in structure and properties of the Quaternary benzophenanthridine alkaloids sanguinarine and cheleritrin.
Sanguiritrin has a wide range of antimicrobial activity, acts on gram-positive and gram-negative bacteria, yeast and micellar fungi. Active against antibiotic-resistant strains of microorganisms. In therapeutic doses it acts bacteriostatically. The mechanism of antimicrobial action of the drug Sanguiritrin is the inhibition of bacterial nuclease, disruption of the permeability of cell walls, division septa, nucleotide structure.
As a preventive measure: newborns to prevent purulent-inflammatory skin diseases and surgical patients – to prevent wound infection.
As a treatment: for infectious and inflammatory diseases of the skin and mucous membranes of bacterial and fungal etiology, including Candida albicans; in dentistry – for periodontitis, aphthous stomatitis, ulcerative-necrotic gingivostomatitis and other lesions of the oral mucosa; in otolaryngology – for sore throat, diseases of the middle ear and external auditory canal; in surgery – for infected burns, wounds that do not heal for a long time, and ulcers; in gynecology – for endocervicitis, colpitis, vaginitis, cervical erosion; in dermatology – at pyodermas, superficial blastomycoses, dermatomycoses.
Hypersensitivity to the components of the drug, fungal lesions with the phenomena of eczematization. Diseases of the liver and kidneys with impaired function.
Special security measures
Do not allow the drug to get on the mucous membranes of the eyes. In case of contact with eyes, rinse immediately with plenty of water.
Method of application and dosage
The drug should be applied externally and topically.
Newborns should be treated with the drug skin folds 2 times a day for the first 5-6 days of life with a sterile cotton swab.
Periodontitis is treated after removal of dental plaque and cleaning of pathological gingival pockets. In the gingival pockets enter for 20 minutes thin turundy, abundantly moistened with the drug or its aqueous solution. Prepare an aqueous solution of the drug immediately before use. To prepare the aqueous solution, dilute the drug 40 times (1 teaspoon per 200 ml of warm boiled water). Repeat the procedure daily or every other day. The course of treatment is 4-6 procedures.
At stomatitis of various etiology on a zone of defeat of a mucous membrane of an oral cavity to make application of drug 2-3 times a day within 2-5 days. Children over 5 years of age should be rinsed with a warm aqueous solution of the drug. For children under 5 years of age with stomatitis, lubricate the oral mucosa with an aqueous solution of the drug.
At a sore throat to treat tonsils once a day within 2-5 days. In addition, adults and children over 5 years of age should be rinsed 3-5 times a day with a warm aqueous solution of the drug. For children under 5 years of age, lubricate the oral mucosa with this solution 3-4 times a day. The duration of treatment is 3-7 days.
At an external otitis to enter in an auditory pass the turundas moistened with drug, for 10-15 minutes 2-3 times a day. The minimum course of treatment is two weeks. In chronic purulent otitis media, the drug should be instilled in adults 5-8 drops 2-3 times a day, children – 1-2 drops 3-4 times a day.
To prevent purulent-inflammatory complications, treat the wound daily with a sterile gauze swab soaked in the drug, cover with a sterile napkin soaked in it, and apply a bandage. After 3-4 days, re-treat the wound with the drug and apply a dry sterile bandage. The course is determined by the course of wound healing, with an uncomplicated course, the period of application is 7-10 days.
For the treatment of infected burns, wounds and ulcers that do not heal for a long time, open infected fractures, use an aqueous solution of the drug. Rinse wounds and ulcers with an aqueous solution of the drug, as well as apply bandages with the solution to the wound surface. For infected burns, bandaging should be done every other day, for other wounds – 1-2 times a day. The duration of treatment depends on the nature and severity of the disease.
At endocervicitis, colpitis, vaginitis, cervical erosions do douching, irrigation and lotions with a warm aqueous solution of the drug 1-2 times a day. The course of treatment is 5-10 procedures.
In pyoderma, superficial blastomycosis and dermatomycoses, including those complicated by mixed flora, the drug should be prescribed in the form of bandages or lubrication of the lesion 1-2 times a day. The duration of treatment is determined by the nature and severity of the disease.
The drug can be used in children, including newborns.
In case of overdose may increase the side effects of the drug. Treatment – symptomatic therapy.
From the immune system: allergic reactions, including redness.
When applied to the mucous membranes of the oral cavity – a feeling of bitterness, and when applied to the wound surface – a short-term burning sensation.
Store in the original package at a temperature not exceeding 25 ° C. Keep out of reach of children.