Sanorin (naphazoline nitrate) nasal spray 1 mg/ml. 10 ml. vial


Manufacturer: Czech Republic

Acute rhinitis. As an adjunct to inflammation of the paranasal sinuses and middle ear.


Sanorin (naphazoline nitrate) nasal spray 1 mg/ml. 10 ml. vial


active ingredient: naphazoline nitrate;

10 ml of solution contains 10 mg of naphazoline nitrate;

excipients: boric acid, ethylenediamine, methyl paraben (E 218), purified water.

Dosage form

Nasal spray, solution.

Basic physical and chemical properties: transparent, colorless solution, odorless.

Pharmacological group

Decongestants and other drugs for topical use in diseases of the nasal cavity. Sympathomimetics, simple.
Code ATX R01A A08.

Pharmacological properties

Naphazoline is a drug that stimulates the sympathetic nervous system and acts on β-adrenoceptors, has minimal effect on β-adrenoceptors. Due to the vasoconstrictive effect, edema, hyperemia, and exudation are reduced, which facilitates nasal breathing in rhinitis. Nafazolin helps to open and expand the outlet ducts of the paranasal sinuses and Eustachian tubes, which improves the outflow of secretions and prevents the deposition of bacteria.
The therapeutic effect of intranasal use occurs within 5 minutes and lasts 4-6 hours.


Acute rhinitis. As an aid in inflammation of the paranasal sinuses and middle ear.


Hypersensitivity to the active substance or to any component of the drug.
Dry inflammation of the nasal mucosa.
Do not use in children under 15 years.

Method of application and dosage

Adults and children over 15 years of age apply 1-3 irrigations in each nasal passage 3 times a day with an interval of at least 4 hours.
It is not recommended to use Sanorin nasal spray longer than 3 days for children over 15 years and longer than 5 days for adults.
If nasal breathing is facilitated, use can be stopped earlier.
Sanorin can be re-applied only after a few days.


Use for children over 15 years.


Overdose or accidental ingestion of the drug can cause systemic side effects: nervousness, sweating, headache, tremor, tachycardia, palpitations, hypertension. Cyanosis, nausea, fever, spasms, cardiac arrest, pulmonary edema, mental disorders, pale skin, heart attack may occur.
Depressant effect on the central nervous system is manifested by symptoms such as fever, bradycardia, sweating, drowsiness, shock, similar to hypotension, apnea, coma. The risk of overdose increases in children who are more vulnerable to adverse effects than adults.
Treatment is symptomatic.

Side effects

When used in the recommended doses, Sanorin is usually well tolerated. In patients with hypersensitivity, the drug may occasionally cause burning and dryness of the nasal mucosa. In isolated cases, there may be a feeling of severe nasal congestion.
Only in isolated cases there is a systemic side effect (most often in case of overdose):

  • From the immune system: allergic reactions, including Quincke’s edema, burning.
  • From the nervous system: nervousness, headache, tremor.
  • From the cardiac system: tachycardia, palpitations.
  • From the vascular system: hypertension.
  • From the skin and subcutaneous tissue: increased sweating.

Prolonged (longer than 5 days for adults and longer than 3 days for children) or frequent use of the drug can lead to addiction – sanorinism, accompanied by intense swelling of the nasal mucosa, which occurs in a relatively short period of time after use. Prolonged use of the drug can damage the epithelium of the mucous membrane, inhibit the activity of the epithelial cilia and cause irreversible damage to the mucous membrane and the development of dry rhinitis.