Acute rhinitis. As an adjunct to inflammation of the paranasal sinuses and middle ear.
active substance: naphazoline nitrate;
1 ml of solution contains 0.5 mg of naphazoline nitrate;
excipients: boric acid, ethylenediamine, methylparaben (E 218), purified water.
Nasal spray, solution.
Sanorin Pharmacological properties
Naphazoline is a drug that stimulates the sympathetic nervous system and acts on -adrenoceptors, has minimal effect on β-adrenoceptors. Due to the vasoconstrictive effect, edema, hyperemia, and exudation are reduced, which facilitates nasal breathing in rhinitis. Nafazolin promotes the opening and expansion of the outlet ducts of the paranasal sinuses and Eustachian tubes, which improves the outflow of secretions and prevents the deposition of bacteria.
The therapeutic effect of intranasal use occurs within 5 minutes and lasts 4‒6 hours.
Acute rhinitis. As an aid in inflammation of the paranasal sinuses and middle ear.
Hypersensitivity to the active substance or to any component of the drug.
Dry inflammation of the nasal mucosa.
Do not use in children under 3 years.
Method of application and dosage
For children aged 3 to 6 years, apply 1-2 irrigations in each nasal passage, for children aged 6 to 15 years – 2 irrigations in each nasal passage.
Sanorin should be used 3 times a day, but not more often than after 4 hours.
Sanorin should not be used for more than 3 days.
If nasal breathing is facilitated, use can be stopped earlier.
Sanorin can be re-applied only after a few days.
Use for children over 3 years.
Overdose or accidental ingestion of the drug can cause systemic side effects: nervousness, sweating, headache, tremor, tachycardia, palpitations, hypertension. Cyanosis, nausea, fever, spasms, cardiac arrest, pulmonary edema, mental disorders, pale skin, heart attack may occur.
Depressant effect on the central nervous system is manifested by symptoms such as fever, bradycardia, sweating, drowsiness, shock, similar to hypotension, apnea, coma. The risk of overdose increases in children who are more vulnerable to adverse effects than adults.
Treatment is symptomatic.
In patients with hypersensitivity, the drug may occasionally cause burning and dryness of the nasal mucosa. In isolated cases, a feeling of severe nasal congestion may occur.
Only in isolated cases there is a systemic side effect (most often in case of overdose):
- From the immune system: allergic reactions, including Quincke’s edema, burning.
- From the nervous system: nervousness, headache, tremor.
- From the cardiac system: tachycardia, palpitations.
- From the vascular system: hypertension.
- From the skin and subcutaneous tissue: increased sweating.
Prolonged or frequent use of the drug can lead to addiction – sanorinism, accompanied by intense swelling of the nasal mucosa, which occurs in a relatively short period of time after application. Prolonged use of the drug can damage the epithelium of the mucous membrane, inhibit the activity of the epithelial cilia and cause irreversible damage to the mucous membrane and the development of dry rhinitis.
Storage conditions Sanorin
Store in the original package in order to protect from light, at a temperature not exceeding 25 ° C, out of reach of children. Do not freeze.