Vulvovaginal mycoses caused by fungal infections that are sensitive to econazole.
Santecvin Composition and form of release
Main active ingredient: econazole nitrate.
The excipients included in the preparation: adeps solidus, polysorbate, triethylene glycol, triethanolamine.
It is produced in the form of intravaginal pessaries, in a dosage of 150 mg of econazole.
This drug is included in the group of antimicrobial, antiseptic drugs used in gynecology as an antimycotic agent.
The main active ingredient is econazole. It is a triazole fungicide.
Has an antifungal effect against dermatophyte-type fungi, as well as yeast and moldy fungi.
It also shows activity against bacteria of the gram-positive and gram-negative series.
The mechanism of action is due to the ability to damage the cell membranes of the fungus through the property of increasing the permeability of the cells of the microorganism and damage the intracellular membranes inside the cytoplasm.
Reaches the maximum concentration 24-48 hours after the first injection of the drug, depending on the dosage used.
It is intended for the use of the drug for the treatment of certain diseases of the vagina. In particular, they are used in the treatment of vulvovaginal mycoses caused by pathogens of fungal infections sensitive to econazole.
The drug in question is contraindicated for use in cases where the patient has severe hypersensitivity (allergy) to the main or to one of the auxiliary components.
You should not violate the rules for the use of this medicinal pharmaceutical product.
Not for oral use.
This medication should not be combined with other intravaginal preparations based on mineral oils, vegetable oils or petroleum jelly.
The level of blood clotting should be monitored while taking it with oral anticoagulants such as warfarin, acenocoumarol and phenprocoumon.
Simultaneous use with barrier contraceptives should be avoided, as the drug can weaken their effect.
Application during pregnancy and lactation
This drug can be used in the treatment of pregnant women only in the 2nd and 3rd trimesters of pregnancy, if absolutely necessary.
If it is necessary to take the drug during breastfeeding, lactation is suspended.
Method of administration and dosage
When using pessaries at a dosage of 150 mg, 1 pessary is prescribed 1 time per day, at night, for 3 days. Treatment continues until the symptoms of itching disappear. The drug is administered before going to bed, after removing the packaging from the pessary and inserting it deeper into the vagina.
In case of relapse, or if culture analysis showed a positive result 1 week after treatment, a second course of treatment should be carried out.
Overdose was not observed due to the low toxicity of the components of the drug.
Theoretically, an overdose can cause an increase in adverse reactions.
However, accidental ingestion may increase side effects.
Accidental ingestion can cause:
- nausea, vomiting;
- diarrhea, headache.
In case of an overdose, symptomatic treatment is recommended – gastric lavage, intake of enterosorbents.
The effectiveness of hemodialysis has not been studied. No specific antidote has been identified.
The drug is usually well tolerated.
In some cases, side effects such as:
- hypersensitivity reactions in the form of itching, erythema;
- angioneurotic edema, allergic urticaria, contact dermatitis;
- dryness and flaking of the skin;
- burning sensations in the body;
- pain at the site of administration, hyperemia.
In case of undescribed side effects, you should consult a doctor.
Storage conditions and periods Santecvin
Expiration date – up to 3 years from the production date indicated on the package.
The storage temperature should not exceed 30 ° C.