Sedafiton (extracts of valerian, motherwort, hawthorn) tablets №48


Manufacturer: Ukraine

Mild forms of neurotic disorders accompanied by irritability, anxiety, fear, depression, increased fatigue, inattention, increased nervous excitability; mild forms of sleep disorders associated with excitement; attacks of headache, migraine caused by nervous tension; mild forms of dysmenorrhea, climacteric syndrome; neurocirculatory dystonia with tachycardia, cardiac pain and arterial hypertension; stage I arterial hypertension; as part of complex therapy and prevention of chronic ischemic heart disease, atherosclerosis, arterial hypertension, supraventricular and ventricular arrhythmias, initial stages of chronic heart failure; dermatoses accompanied by skin itching (urticaria, atopic dermatitis, eczema); constant mental stress (manager’s syndrome).

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Sedafiton (extracts of valerian, motherwort, hawthorn) tablets №48


active substances: 1 tablet contains: valerian rhizomes with roots of thick extract (Valerianae radix cum radicibus) (1:2.5) (extractant – ethanol 40%) 0.05 g, motherwort grass extract thick (Leonuri herba) (1:3 ,0) (extractant – ethanol 40%) 0.03 g, hawthorn fruit extract thick (Сrataegi fructus) (1:1.7) (extractant – ethanol 70%) 0.03 g;

excipients: heavy magnesium carbonate, potato starch, povidone, talc, magnesium stearate.

Medicinal form


The main physicochemical properties: tablets that are solid regular round cylinders, the upper and lower surfaces of which are convex, from greenish-gray, gray, brownish-gray to grayish-green, grayish-brown in color with light and dark multi-colored inclusions.

Pharmacotherapeutic group

Sleeping pills and sedatives.
ATX code N05C M.

Pharmacological properties

This drug belongs to the group of natural remedies, which are used as a hypnotic and sedative, mainly in the complex treatment of diseases associated with increased excitation of the nervous system.
The active components of the drug are extracts of valerian, motherwort, hawthorn. These drugs have long been used in traditional medicine.
The sedative properties of these plants are explained by the presence in them of a rich complex of various components – stachydrins, essential oils, steroid glycosides, ascorbic acid, saponins, bitterness, and mineral salts.
In general, the effect of the drug is similar to that of valerian. It effectively treats cardiovascular diseases, and is also used for the prevention of such diseases. The substances that make up the motherwort herb produce an antispasmodic, analgesic, hypotensive, sedative, diuretic, carminative, cardiotonic effect.
Has the ability to reduce pressure, slow breathing, reduce the number of myocardial contractions, suppress fears, improve the quality of sleep. Increase endurance with a lack of oxygen, help lower blood cholesterol levels.


Most often, this drug Sedafiton tablets №48 is used in the complex treatment of diseases of the nervous system, acts as a sedative, relieves nervous tension, convulsions.
In particular, they are used for:

  • increased nervous excitability, with neurasthenia, depression, during stress;
  • neuroses of a cardiovascular nature;
  • early stages of arterial hypertension;
  • mild insomnia, sleep disturbances;
  • during menopause, with asthenia.

Before starting treatment, you should consult your doctor.


The drug Sedafiton tablets №48 in question is contraindicated for use in cases where the patient has severe hypersensitivity (allergy) to the main or to one of the auxiliary components.
Also contraindicated in arterial hypotension and bradycardia.
It should be borne in mind that taking motherwort enhances the pharmaceutical effect of hypnotics, analgesics, cardiac glycosides, antihypertensive drugs, alcohol.
It is not used in pediatrics until the age of 12.

Application during pregnancy and lactation

This drug Sedafiton tablets №48 is contraindicated for pregnant women and during lactation.
Its use promotes the stimulation of smooth muscles in the uterus. For this reason, it is dangerous to use it during pregnancy. this can lead to premature birth or spontaneous abortion.

Method of administration and dosage

The drug Sedafiton tablets №48 is taken orally, three or four times a day, 1-2 tablets, depending on the doctor’s prescription.
You can take a dose 2-3 times a day. For milder forms of insomnia, it is recommended to take 1 or 2 tablets 60 minutes before going to bed.
It should be noted that the safe daily dose is no more than 6 tablets per day.
The duration and correction of the dosage and duration of admission, the expediency of repeated courses of treatment is determined by the doctor individually.
The patient should consult a doctor if the symptoms of the disease did not disappear during the use of the medicinal product or if adverse reactions are observed that are not indicated in the instructions for medical use of the medicinal product.


Overdose may cause some side effects. In particular:

  • dizziness, drowsiness, lethargy;
  • constriction in the chest, bradycardia or tachycardia, lowering blood pressure;
  • mental agitation.

In case of an overdose, immediately rinse the stomach, take enterosorbents.

Side effects

Usually, this drug is well tolerated without causing complications.
The use of this drug may occasionally cause allergic side reactions, in particular, such as:

  • allergic urticaria, itching, rash, hyperemia;
  • nausea, vomiting, diarrhea, angioedema;
  • peripheral edema, shortness of breath, headache;
  • dyspeptic symptoms.

Reactions from the nervous system may also occur – dizziness, drowsiness, a feeling of fatigue, decreased performance, memory acuity, mnemonic abilities.
In addition, it is possible:

  • dizziness, drowsiness, weakness;
  • depression, depressed state of mind;
  • bradycardia, tachycardia, pressure reduction.

If side effects occur, the drug should be discontinued, symptomatic therapy should be undertaken, consult a doctor and the treatment regimen should be adjusted.