Treatment of essential arterial hypertension in adults and children over 6 years of age. Treatment of kidney disease in adult patients with arterial hypertension and type II diabetes mellitus with proteinuria ≥ 0.5 g / day – as part of antihypertensive therapy. Treatment of chronic heart failure (in patients aged 60 years and older), when the use of ACE inhibitors is considered impossible due to incompatibility, especially when coughing, or is contraindicated. Patients with heart failure whose condition has stabilized with the use of an ACE inhibitor should not be transferred to treatment with losartan. The patient’s left ventricular ejection fraction should be ≤ 40 %, the condition should be clinically stable, and the patient should adhere to the established treatment regimen for chronic heart failure. To reduce the risk of stroke in adult patients with hypertension and left ventricular hypertrophy, confirmed by ECG.